My recollection is that gamma-chymotrypsin crystals will persist in
pHs all the way from 3 to 9.  I don't know if the crystals will grow
over that range.

   There are a fair number of phage T4 lysozymes variants in the PDB.  I
don't think this is considered "overpopulation" but a valuable
contribution to humanity.  ;-)

Dale Tronrud

On 9/19/2019 4:03 PM, Murpholino Peligro wrote:
> A quick glance at the entries of hen egg white lysozyme in the PDB show
> that it can be crystallized at different pH values, but the space group
> is not always the same. I still have to refine the analysis but I was
> wondering that maybe there are a few proteins that can crystallize at a
> wide range (maybe not that wide) of pH values and still have the same
> space group?
> 
> To refine the analysis a wee further: By any chance do you know any
> proteins overpopulating the PDB (i.e. besides HEWL)?
> 
> Lots of thanks as always.
> 
> Murphy
> 
> 
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