> if you're in even vaguely warm or temperate regions (or seasons), cooling > the intake air to 4C brings it to below dew point, and then condensation > and snow are guaranteed.
I once serviced a robot in a 4C room in Singapore, which didn't seem to have any kind of dehumidification - or maybe it had broken down. Water was running feely down the walls and poling on the floor, and the robot was covered in condensation. Every non-stainless screw on the controller, computer, robot etc was rusty. Interestingly, both the robot and the computer still worked. Patrick On Wed, Sep 25, 2019 at 6:04 AM Frank Von Delft <frank.vonde...@sgc.ox.ac.uk> wrote: > My colleague Opher Gileadi gave us an excellent tip when we were designing > our 4C harvesting room, over a decade ago: *set it to 7C*. The crystals > are unlikely to mind, but it's SO much more comfortable to be in for > hours. > > I seem to remember he mentioned something like a comfort inflection point > as you approach 4C. > > *Install low-flow fans*. Fridge people seem to default to installing > hurricane machines, you have to tell them that a very very small flow is > enough. > > *Get strong light* - probably even those daylight things (we don't have > them). Being cold is miserable enough already, there's no need to compound > it with weak light. > > *Vibration* - that dwindles to insignificance if the air flow goes down. > > *Humidity* - we installed (at considerable expense) a low humidity air > supply - really hard to know just how much it helps, but a few years ago > when I had it turned it off to help save energy, very quickly I heard > complaints about snow in the liquid nitrogen becoming a major hassle. So > based on that set of anecdotes, I conclude it probably *is* worth having > dry air. > > It's *much* cheaper though if they can design it into the building's > infrastructure, if it's a new building; retrofitting turned out to be > super expensive (in our case). > > As dry as possible. Look at and understand the psychrometric chart > (google it): if you're in even vaguely warm or temperate regions (or > seasons), cooling the intake air to 4C brings it to below dew point, and > then condensation and snow are guaranteed. > > *Size* - make it as big as you can get away with, with lots of bench and > shelf space. Your students will already be miserably cold, no need for > them to be cramped too. > > Good luck! > Frank > > > > > > On 24/09/2019 23:40, Scott, Emily wrote: > > Anyone out there specifically design rooms for (protein) crystallization > at ~22 deg and 4 deg C? If you have successes or failures and can share > any design specs with regard to vibration, temperature, and humidity > tolerances, it would be much appreciated to pass on to the architects for > our new laboratory. > > > > Sincerely, > > Emily Scott > > > > -- > > Emily Scott, Ph.D. > > Professor, Medicinal Chemistry/Pharmacology/Biophysics > > Faculty Director, BioNMR Core Lab > > University of Michigan > > 428 Church Street > > Ann Arbor, MI 48109-1065 > > Phone: 734-764-3530 > > https://pharmacy.umich.edu/people/scottee > > Lab webpage: http://scottlab.info > > > > > > ********************************************************** > Electronic Mail is not secure, may not be read every day, and should not > be used for urgent or sensitive issues > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > > > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > -- patr...@douglas.co.uk Douglas Instruments Ltd. Douglas House, East Garston, Hungerford, Berkshire, RG17 7HD, UK Directors: Peter Baldock, Patrick Shaw Stewart http://www.douglas.co.uk Tel: 44 (0) 148-864-9090 US toll-free 1-877-225-2034 Regd. England 2177994, VAT Reg. GB 480 7371 36 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
