?Hi Lei,

Rosetta uses something very similar to this for designing proteins that bind to 
ligands/proteins. Perhaps look there.


Best wishes,
Reza


Reza Khayat, PhD
Assistant Professor
City College of New York
Department of Chemistry
New York, NY 10031
________________________________
From: CCP4 bulletin board <[email protected]> on behalf of Zheng, Lei 
<[email protected]>
Sent: Wednesday, January 8, 2020 10:57 AM
To: [email protected]
Subject: [EXTERNAL] [ccp4bb] Searching similar local structural conformations

Dear CCP4ers,

We identify a potential ion binding site formed by four residues in a 
structure. I want to search if any other structures have a similar local 
residual geometry. Is there any programs to perform such a searching? For 
example, to search in Protein Data Bank using coordinates of the binding site 
residues? I appreciate your suggestions.

Happy New Year!
Lei



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