Dear Armando,

in case you have enough material to spare, I would use a concentrator to 
create a saturated solution, i.e. concentrate until it precipitates. Measure 
the concentration of the saturated solution, i.e., supernatant without 
disturbing the solution with the precipitate.

You can start crystallisation trials at 70-90% of this concentration.

Best,
Tim

On Wednesday, January 8, 2020 5:16:31 PM CET Armando Albert wrote:
> Dear all,
> I was wondering how to guess the optimal protein concentration for the
> initial crystallisation trials. Is there any trick or assay other than the
> classic PCT from Hampton? Armando
> 
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Tim Gruene
Head of the Centre for X-ray Structure Analysis
Faculty of Chemistry
University of Vienna

Phone: +43-1-4277-70202

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