Full time, fixed term contract until 31 December 2021.

https://www.jobs.ac.uk/job/BXB907/research-fellow-78236-119

Funding at level 6 is available for a maximum 18 months restricted to end by 31 
December 21

CHNUK: Structural approaches to novel fragment based and natural product 
antibiotic discovery

Applications are invited for a highly motivated and experienced postdoctoral 
researcher to join an active research group at the School of Life Sciences, 
University of Warwick supervised by a team headed by Prof Chris Dowson. The 
project, which has been recently funded by the Newton Fund, focuses on 
acquiring specific structural and biochemical data using a novel strategy of HT 
affinity crystallography, using robust crystals of well validated and novel 
antibacterial targets to identify either fragment-based inhibitors or 
inhibitors identified by crystallography directly from complex mixtures of 
natural products. This position is available for up to 18 months in the first 
instance and will involve substantive interactions with academic colleagues at 
Harwell (Prof Frank vonDelft) and those in China at the Shanghai synchrotron.

You will have a PhD in a relevant field. The successful applicant should have 
proficiency in molecular cloning, protein expression, purification, 
crystallization, X-ray crystal structure determination in particular and should 
have a background in biochemistry or molecular biology/ drug discovery 
generally.

The School of Life Sciences at Warwick is equipped with state-of-the-art 
protein expression and purification apparatus, including high-throughput 
facilities for crystallisation and visualisation as well as regular synchrotron 
access in the UK and abroad. The wider laboratory is very well equipped with 
microbiological, biochemical and biophysical infrastructure and the successful 
applicant will join a wider team of highly motivated scientists working on a 
range of antimicrobial discovery and resistance projects.

Email: [email protected]

Website: https://warwick.ac.uk/fac/sci/lifesci/research/infdisease.

Closing date: 31 January 2020

Full details of the duties and selection criteria for this role can be found in 
the vacancy advert on the University of Warwick’s jobs pages. You will be 
routed to this when you click on the Apply button below.

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