I honestly think that University facilities ought to open up ‘safely’ for Covid related research and diagnostics
Get Outlook for iOS<https://aka.ms/o0ukef> ________________________________ From: CCP4 bulletin board <[email protected]> on behalf of Frank von Delft <[email protected]> Sent: Thursday, April 2, 2020 10:10:03 AM To: [email protected] <[email protected]> Subject: Re: [ccp4bb] COVID-19 protease inhibitors - 2nd call for designs - Thurs midnight Hi Nick - it is we that thank you all; and apologies for the tight deadlines, all I can say is we'd be a bit more thoughtful but CoV-2 is not being particularly obliging either... There will be at least one more round, deadline approximately one week later; and we may have additional fragments because Diamond came back up this week, just for COVID work. Speaking of which: reminder that if you need a synchrotron or cryoEM for COVID work, you can put in rapid access proposals - details on Diamond's website. (I'll stop spamming the list now - thanks for your forebearance.) Frank On 02/04/2020 01:01, Nicholas Larsen wrote: Hi Frank, I thought we were working quickly, but we only just got all of your structures uploaded in our Proasis system today and can only now begin analysis and design ideas. I don't know if we will have much of anything by your deadline. Will there be additional design rounds? Thanks again for making all this data available and it really is inspirational what your team is doing to confront collaboratively this global crisis. Best, Nick On Wed, Apr 1, 2020 at 10:16 AM Frank von Delft <[email protected]<mailto:[email protected]>> wrote: All - last week's call for compound designs to the CoV-2 main protease (https://covid.postera.ai/covid) elicited an astonishing response... (I confess I was quite taken aback.) I just realised I should let this BB know the second call for designs is now open. Deadline is tomorrow 23:59 PST (April 2nd). (Apologies for those that weren't following on twitter.) Two things: * we're asking for designs especially focusing on covalent inhibitors (read more here<https://discuss.postera.ai/t/screening-cascade-fast-track-and-regular-track-of-designs/567>) * the most convincing designs will be fast-tracked by spending more money to cut several weeks off the testing (read more here<https://discuss.postera.ai/t/screening-cascade-fast-track-and-regular-track-of-designs/567>) Happy designing! Frank ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 [This e-mail message may contain privileged, confidential and/or proprietary information of H3 Biomedicine. If you believe that it has been sent to you in error, please contact the sender immediately and delete the message including any attachments, without copying, using, or distributing any of the information contained therein. This e-mail message should not be interpreted to include a digital or electronic signature that can be used to authenticate an agreement, contract or other legal document, nor to reflect an intention to be bound to any legally-binding agreement or contract.] ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
