Hi Andy, Are you familiar with ProtCID? http://dunbrack2.fccc.edu/ProtCiD/Default.aspx Might be relevant.
Best, Orly On Sun, Jun 21, 2020 at 12:02 AM Andrew Lovering <a.lover...@bham.ac.uk> wrote: > Dear colleagues, > > > I have a structure of a simple, common fold (hth, dna-binding) that I > believe has oligomerized in a different way to that observed for any > members of the superfamily that I can reasonably analyze. > > > So if I run fold comparison analysis (e.g. DALI) it will find similar > structures on the monomeric level but what I really want is it to find hth > structures that place each monomer in a similar position to the monomers of > our tetramer.....this seems harder to do > > [literature searches are slow and all yield tetramers dissimilar in nature > to ours] > > > I can of course "cheat" and turn our tetramer into a monomer (e.g. give > the four chains the same chain ID but different residue ranges) but in > something like DALI this would only get a hit to anything approximating the > tetramer with a single chain protein? (I tried, this seems to be so) > > > I hope its easier than I'm making out and would love to be enlightened! > > Best > > Andy > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 > -- Orly Avraham, Ph.D. Postdoctoral fellow The lab of Prof. Oded Livnah and the lab of Prof. Ora Schueler-Furman The Hebrew University of Jerusalem Israel ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
