Dear CCP4bb,

I'm trying to insert an Acetone molecule between two cysteine residues in
coot or modifying the pdb. I'm working on this modified molecule where the
disulfide bridge was chemichally opened and inserted an acetone molecule
between the two cysteine.

MS data confirm this modification (98% of molecules modified) but I can not
insert the acetone covalently linked to the S of both cysteine
(S-ACN-S).
Maybe what I think and what I am doing is not the right solution (the
disulfide bridge is still alive?) anyway i would like to know how to link
the acetone to the two cysteine
To better understand what I mean in attach you find a screenshot

I thank in advance all those who will have the courtesy to make a suggestion

Daniele Veggi

########################################################################

To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Reply via email to