Hi all

I'm designing genes for expression in M. smegmatis (safe host for Mtb 
proteins), but its not possible (or advisable due to the GC content) to 
optimise for
mycobacterial expression.

Would anyone with experience be able to tell me if its fine to stick with the 
E. coli codon optimisation, or if there is an advantage going with b. subtilis 
(or another G+ organism that is in Thermo's list).

Best wishes

Matthew.

########################################################################

To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Reply via email to