Dear All,
we have a post-Doc position available here at EMBL Grenoble shared
between the high throughput crystallisation team
(https://www.embl.fr/services/ht_crystallisation/index.html) and the
synchrotron team (https://www.embl.fr/research/unit/mccarthy/index.html)
to work with me on the ESRF beamline MASSIF-1
(http://www.esrf.eu/MASSIF1). MASSIF-1 has pioneered fully automated
data collection, including sample location and decision making
algorithms (see https://doi.org/10.1107/S2059798318003728
http://dx.doi.org/10.1107/S1399004715011918
http://dx.doi.org/10.1107/S1600577515016604) This year will see two
exciting upgrades to the beamline - first, the ESRF will be coming back
on-line after completely re-building the accelerator
(https://www.esrf.eu/about/upgrade) as the worlds first high energy
fourth generation synchrotron - ESRF-EBS - we will be upgrading the
beamline optics to maximise the capabilities of the new source. Second,
the experimental station of MASSIF-1 will be completely refurbished to
have a new diffractometer and the revolutionary crystal mounting robot,
CrystalDirect (http://dx.doi.org/10.1107/s2059798316000954
http://dx.doi.org/10.1107/s0907444912031459) will also be installed on
the beamline bringing automation all the way from pure protein to
structure models (see http://dx.doi.org/10.1063/1.5084627)
This is an exciting opportunity to be involved in the commissioning of
an MX beamline at the forefront of automation. This will be a highly
collaborative position working with the EMBL instrumentation, HTX and
synchrotron teams, as well as the ESRF, towards the design, construction
and operation of the upgraded MASSIF-1 beamline with a focus on
expanding its capabilities to support automated fragment screening and
crystallography pipelines. You will also contribute towards the
development of new methods exploiting the unique experimental
opportunities provided by the integration of the CrystalDirect
technology in a beamline environment. You will also participate in
research projects involving fragment screening and development of
chemical tools on targets of biomedical relevance.
Please feel free to contact me, Josan Marquez (marq...@embl.fr) or
Andrew McCarthy (andre...@embl.fr) for informal inquiries - you will
need to apply here
https://www.embl.de/jobs/searchjobs/index.php?nPostingID=1225&nPostingTargetID=2879&ID=QHPFK026203F3VBQB688N79SB
Closing date is the 12th October and interviews will be early November
2020.
Best wishes, Matthew.
--
Matthew Bowler
Synchrotron Crystallography Group
European Molecular Biology Laboratory
71 avenue des Martyrs
CS 90181 F-38042 Grenoble
France
===================================================
Tel: +33 (0) 4.76.20.76.37
Fax: +33 (0) 4.76.20.71.99
http://www.embl.fr/
http://www.esrf.eu/MASSIF1
https://twitter.com/id30_massif1
http://www.embl.fr/research/unit/mccarthy/members/index.php?s_personId=CP-60015559
===================================================
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