Dear Colleagues,

A postdoctoral position is immediately available for a highly motivated 
individual interested in understanding the structural mechanisms of ubiquitin 
signaling.  Research is focused on understanding basic molecular mechanisms of 
the enzymatic machinery responsible for protein ubiquitination, structural 
characterization of PROTAC complexes with potential therapeutic value, and 
structure determination of large protein complexes regulated by ubiquitin 
signaling, particularly those involved in DNA repair.  These issues will be 
addressed using a multidisciplinary approach that includes X-ray 
crystallography and cryoEM complemented with biochemical/biophysical techniques 
and cell based assays.  

Candidates should hold a recently obtained PhD in biochemistry, chemistry, or 
related subject, with demonstrated expertise in X-ray crystallography, cryoEM, 
and/or the biochemical analysis of protein ubiquitination.  Experience with 
protein expression in insect and mammalian cells is a plus.

Interested candidates should e-mail a cover letter, CV, and the names of three 
references to: [email protected].

Shaun K. Olsen
Associate Professor
Department of Biochemistry & Structural Biology
University of Texas Health Science Center at San Antonio
7703 Floyd Curl Drive, BSB413C/414C
San Antonio, TX 78229
Phone: 210-450-3091
E-mail: [email protected]

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