My lab will soon be moving to the University of South Alabama in Mobile and I'm looking to recruit two post docs. One project is structural and functional investigations of mutated forms of penicillin-binding protein 2 (PBP2) from N. gonorrhoeae, with the goal of understanding molecular mechanisms underlying resistance to cephalosporin antibiotics. The other is drug discovery against PBP2 in collaboration with a pharma.
Both projects entail cloning, purification and crystallization of PBP2 variants, collecting diffraction data at synchrotron facilities, solving structures by X-ray crystallography, site-directed mutagenesis, enzyme kinetics and various biophysical techniques. Candidates should hold a PhD in biochemistry or chemistry, with a strong background in molecular biology, protein crystallography, and preferably enzyme kinetics. An interest in antibiotic resistance and antimicrobial drug discovery is desirable. The candidate will be highly motivated to succeed, able to think critically, and work both independently and collaboratively. Good verbal and written communication skills are essential. The University of South Alabama is a comprehensive research and teaching university located in Mobile, Alabama. Its College of Medicine has 270 faculty members across 17 academic departments, with outstanding cores and facilities for research, including a BSL-3 facility for infectious disease research. Mobile (pronounced moh-BEEL) is near the Gulf Coast with ready access to beaches, is only two hours from New Orleans, and is one of most arboreal towns I've seen. Please send cover letter and CV directly to me - Christopher Davies ([email protected]<mailto:[email protected]>) Informal enquiries are welcome. https://gradfacultyresearch.musc.edu/#/davies ***************************************** Christopher Davies, PhD Professor, Dept. of Biochemistry & Molecular Biology, Interim Chair, Department of Oral Health Sciences, Assistant Provost for Research Infrastructure, MUSC Cores Director, Medical University of South Carolina, Charleston SC 29425 Tel: (843) 876 2302 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
