Hi Wajahat,

first off, there is a dedicated mailing list for Phenix specific questions (
http://phenix-online.org/).

You need to run more than one refinement cycle before you try making sense
of R factors.

Pavel

On Wed, Jan 20, 2021 at 10:05 AM Wajahat ali khan <wjt.ali.k...@gmail.com>
wrote:

> Dear all,
>
>
> I have just started with X-ray diffraction.
> I would appreciate any ideas as to why after one cycle of phenix.refine ,
> the Rfree value increased for my ligand fitted model molecular replacement
> solution model.
>
> Thanks
>
> Wajahat
>
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