Dear CCP4 friends

We are looking for fresh talent :) please see the posting below or directly
at MassBio.

https://careers.massbio.org/jobs/?keywords=Research+Associate+Silicon+Therapeutics&location=Boston%2C+MA%2C+United+States&location_completion=city%3DBoston%24state%3DMassachusetts%24country%3DUnited+States&location_type=city&location_text=Boston%2C+MA%2C+United+States&location_autocomplete=true&radius=320


Artem


Silicon Therapeutics (“SITX”) is a privately held, physics-driven
integrated drug discovery company. SITX’s discovery efforts as well as
physics-based platform are all completely in-house, with a full wet lab as
well as a team of experienced R&D professionals spanning biology,
biochemistry, chemistry, biophysics (NMR + X-ray) & preclinical sciences.
SITX’s engine leverages quantum mechanics and molecular dynamics, which are
deployed on its own internal supercomputer composed of over 400 GPU’s and
FPGA’s and allows SITX to accurately simulate the physical motion and
properties of biological targets at an atomistic level resolution. We are
the only company that owns the entire spectrum of physics-driven drug
discovery from chip-to-clinic with a team of over 60 individuals in Boston.

Our diversity and our cross-functional, multi-dimensional teams make us
strong. We foster an open-minded culture where we come to work without
preconceptions about how people think. With all channels open for
communication, we can rapidly fuse information across disciplines and teams.

Job Summary

Silicon Therapeutics is seeking an energetic, passionate practitioner of
the laboratory arts to join the Biochemistry/Biophysics/Structural Biology
platform as a Research Associate . This is a foundational support role for
someone who enjoys technical challenges and is not afraid to get their
hands dirty by helping with core lab functions from cell culture, protein
purification, or biochemical experiments all the way to laboratory
automation, instrument maintenance, etc. The qualified candidate will have
basic laboratory practices under their belt and would be passionate to
learn additional techniques while supporting a growing group dedicated to
Discovery research. The successful candidate will work as part of a
collaborative team of scientists with expertise in protein production,
biochemistry, structure, and biophysics supporting hit-ID, hit-to-lead, and
lead-ID phases of our innate immuno-oncology drug discovery programs and
will have opportunities to learn cutting edge techniques.

Job Responsibilities

Responsible for bacterial and eukaryotic cell culture for the purpose of
recombinant protein expression.
Basic protein purification under supervision of expert practitioners.
Preparation of common biochemical reagents, maintenance of lab readiness.
Biochemical/biophysical characterization of recombinant proteins
Work as part of a cross-functional project team(s) to provide timely,
robust, high-impact results.
Carefully document research workflows, data and protocols using an
electronic laboratory notebook.
Capture experimental results in database.
Organize and present data as needed
Other duties as assigned


Requirements

A minimum of B.Sc. with 2+ years of research experience
Documented experience with recombinant protein production
Propensity towards tinkering with complex equipment
Ability to multitask on the job, combining diligence and tenacity to thrive
in a highly malleable and fluid research environment
Demonstrated ability to execute experiments independently and under the
supervision of experts.
Passion for supporting teams and learning on the job.
Excellent communication skills.
Silicon Therapeutics provides equal employment opportunities to all
employees and applicants for employment and prohibits discrimination and
harassment of any type without regard to race, color, religion, age, sex,
national origin, disability status, genetics, protected veteran status,
sexual orientation, gender identity or expression, or any other
characteristic protected by federal, state or local laws.

Job Information

Job ID: 55846631
Location:
Boston, Massachusetts, United States
Position Title: Research Associate, Biochemistry/Biophysics/Structural
Biology
Company Name: Silicon Therapeutics
Job Function: Scientist
Job Type: Full-Time
Job Duration: Indefinite
Min Education: BA/BS/Undergraduate
Min Experience: 2-3 Years
Required Travel: None


Silicon Therapeutics (“SITX”) is a privately-held, physics-driven
integrated drug discovery company in the preclinical IND stage targeting
innate immunity to start, but with the capability to move into many other
franchise opportunities. The Company’s initial pipeline is focused on
modulation of the innate immune system to “light the spark” within
immunologically cold tumors by using its physics-enabled drug discovery
engine.

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