Dear colleagues,

The Section of Structural Biology of Membrane Proteins in the Laboratory of 
Cell Biology, Center for Cancer Research, National Cancer Institute, NIH has an 
opening for Postdoctoral Fellow with a recent Ph.D. in Biology and training in 
cryo-EM and/or X-ray crystallography. This individual will be working on 
"Mechanistic investigation of cellular drug resistance ".  The project involves 
structural studies of cytosolic and mitochondrial proteins that are targets of 
antimicrobial compounds.  It is anticipated that multiple structural techniques 
will be employed, involving the use of X-ray crystallography and Cryo-EM to 
illuminate structural aspects of target protein’s response to drug treatment.  
Our group has assured access to a synchrotron beam line at APS and to an 
intramural EM facility equipped with an FEI Krios microscope and Gatan K3 
detector. The successful candidate should have practical experiences in 
molecular biology and protein purification for target protein production. 
Experience in mitochondrial proteins is a plus. NIH has a welcoming, 
collaborative and vibrant environment for biomedical research. Our campus is 
located in Bethesda, Maryland. Interested individuals should send their 
Applications, consisting of a CV, a statement of research interest, and three 
letters of recommendation, to Dr. Di Xia via Email at 
[email protected]<mailto:[email protected]>

Best wishes,

Di Xia, Ph.D. Senior Investigator

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