Dear Colleagues, H3 Biomedicine is at the forefront of cancer genomics and drug discovery ( www.h3biomedicine.com). Structural biology plays a prominent role in underpinning our mechanistic understanding of disease biology and empowering our drug design.
We have an exciting opportunity for a postdoc position in structural biology. The qualified candidate will be an outstanding protein chemist with a PhD in structural biology with previous training in cryo-EM (preferred) or X-ray crystallography. Previous publication in structural biology is preferred. The candidate will assist with a range of projects in our oncology portfolio from early to late stage with numerous opportunities for publication. These projects include elucidating the structures of large proteins (>150 KD) and protein complexes that will provide new insights into protein function and cancer biology. To enable these projects, H3 has invested in a GPU workstation for in house data processing/reconstruction and has entered into relationships with both U Mass and Nanoimaging for data collection. The successful candidate will also be encouraged to collaborate and consult with academic advisors as needed. We desire an individual with attention to details, motivation, independence, and ambition to further our mission to improve patient lives. *Basic qualifications:* · Construct design · Expression systems (E coli, insect cells, and mammalian) · Experienced AKTA user · Western Blots · Cross-linking techniques · Sample prep for Negative stain and Cryo-EM data collection · Data processing (particle picking, 2-D classification, 3-D reconstruction, Model Building, Refinement) · Software CCP4, CCP-EM, RELION, cisTEM, Coot, Pymol · Excellent written and verbal communication skills · Nice to have: crystallization techniques (basics screening, optimization, seeding, soaking, harvesting, freezing) Apply at: https://www.h3biomedicine.com/careers/postdoctoral-position-in-structural-biology/ -- <https://www.h3biomedicine.com/> Jiyuan Ke Investigator II Lead Discovery H3 Biomedicine Inc. office +1 (617) 252-3923 <(617)+252-3923>| cell +1 h3biomedicine.com <https://www.h3biomedicine.com/> [image: Tw] <https://twitter.com/h3biomedicine> [image: In] <https://www.linkedin.com/company/2277767> -- [This e-mail message may contain privileged, confidential and/or proprietary information of H3 Biomedicine. If you believe that it has been sent to you in error, please contact the sender immediately and delete the message including any attachments, without copying, using, or distributing any of the information contained therein. This e-mail message should not be interpreted to include a digital or electronic signature that can be used to authenticate an agreement, contract or other legal document, nor to reflect an intention to be bound to any legally-binding agreement or contract.] ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
