Dear CCP4 colleagues, You are cordially invited to the Center for Biomolecular Structure (virtual) lecture series,
An odyssey in drug delivery study via X-ray microscopy approach Dr. Yang Yang National Synchrotron Light Source II June 16, 2021, 13:30 (EDT) Registration Link: https://bnl.zoomgov.com/meeting/register/vJItfuuurzsjG-VF9klmmilw7nbOH8Qcy5s Abstract We’ve used X-ray fluorescence microscopy (XRF) as a powerful chemical nano-imaging tool to study a few examples of anti-cancer drug with transition metal complexes (Os, Ir) and locate their target sites within human cancer cells. Throughout these studies, despite its high sensitivity, semi-quantitative, and versatility, XRF has also complemented other techniques such as soft X-ray microscopy, TEM, cryo light confocal microscopy, and hard X-ray phase contrast imaging to provide more complete pictures to uncover the potential delivery mechanisms. In addition, sample preparations including cryogenic preparation, as well as the transfer compatibility between various techniques, as a critical aspect, will also be discussed. The CBMS Team ------- Vivian Stojanoff, PhD Education, Training, Outreach User Program p 1(631) 344 8375 e [email protected]<mailto:[email protected]> w https://www.bnl.gov/nsls2/lifesciences/<https://www.bnl.gov/ps/lsbr/> Address: Center for Biomolecular Structure National Synchrotron Light Source II Building 745 Brookhaven National Laboratory Upton NY 11973 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
