Yes, I should have mentioned the truncation by estimated RMS error, which was 
part of the protocol we used in the paper with David Baker’s group.  The error 
estimates are calibrated, I believe, for just the C-alpha atoms, so they are 
probably generally underestimates of the errors in the rest of the atoms in a 
residue, particularly the side chains; otherwise, the atom weighting obtained 
by converting the error estimate into an equivalent B-factor would be enough to 
account for errors.

Randy

> On 3 Jul 2021, at 17:36, Adam Simpkin <[email protected]> wrote:
> 
> I agree that RoseTTAFold would be a good idea! We've been looking at the 
> models for MR recently and in many cases they're excellent. We've found it 
> can be useful to truncate the models based on the predicted rms errors with 
> AMPLE (clearer solutions or even the difference between success & failure) so 
> this might be a useful strategy to consider if the models don't work in MR by 
> themselves.  
> 
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-----
Randy J. Read
Department of Haematology, University of Cambridge
Cambridge Institute for Medical Research     Tel: +44 1223 336500
The Keith Peters Building                               Fax: +44 1223 336827
Hills Road                                                       E-mail: 
[email protected]
Cambridge CB2 0XY, U.K.                              
www-structmed.cimr.cam.ac.uk


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