Phos-tag gels are an option (albeit a fiddly one).
Cheers,
Pat Loll

___________________________

Patrick J.  Loll, PhD (he, him, his)
Professor of Biochemistry & Molecular Biology
Drexel University College of Medicine
Room 10-102 New College Building
245 N. 15th St.
Philadelphia, PA 19102-1192 USA

(267) 359-2653
[email protected]


> On 15 Sep 2021, at 8:28 AM, Andrea Moretti <[email protected]> wrote:
> 
> Dear CCP4 community,
> 
> sorry for the off topic question but I am struggling with enzymatic assays 
> and I would need your help.
> 
> I am trying to measure dephosphorylation of a phosphorylated kinase by a 
> ser/thr phosphatase. So far I tried to measure it by malachite green assay, 
> anti pSer/pThr antibody and PNPase coupled assay but nothing really worked 
> for me. NMR is unfortunately not an option since I can't make enough of the 
> proteins.
> 
> So any hints on phosphatase assays would be helpful.
> Thanks!
> 
> Best wishes,
> Andrea
> 
> 
> -- 
> Andrea Moretti
> Structural Plant Biology Laboratory
> Department of Botany and Plant Biology
> Sciences III
> University of Geneva
> 30 Quai E. Ansermet
> 1211 Geneva
> Switzerland
> Email: [email protected]
> Phone: +41 22 379 3029 (office)
> web:http://structplantbio.org
> 
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Patrick Loll
[email protected]




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