Hi Claude,
Pymol 2.4.0 (installed via homebrew) works fine for me in Apple M1 MacBook Pro, 
2020.
Ciao,
S

> On 16 Sep 2021, at 12:12, Claude Sauter <[email protected]> wrote:
> 
> Dear all,
> 
> to continue on the same theme, a colleague biochemist asked me a couple of 
> days ago if there is any incompatibility between PyMOL and other softwares 
> used in structural biology and new mac M1 chips. Being a Linux user, I have 
> no clue. Could mac users share their experience?
> 
> Thanks
> Best regards,
> Claude
> 
> Le 16/09/2021 à 09:40, WENHE ZHONG a écrit :
>> Dear CCP4 community,
>> 
>> The COOT is not running smoothly on my M1 chip Macbook. For example, when 
>> both model and the electron density map are displayed, the moving from one 
>> residue to the next (pressing SPACE bar) is lagging/slow (>2s). This only 
>> happened to my old computer, but I am surprised to find it happens in the 
>> newest macbook.
>> 
>> Anyone have this problem and has a solution? Thanks.
>> 
>> Best regards,
>> Wim
>> 
>> 
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> -- 
> Dr Claude Sauter
> Directeur de Recherche
> Institut de Biologie Moléculaire et Cellulaire (IBMC-ARN-CNRS)
> Biologie des ARNt et pathogénicité      tel +33 (0)388 417 102
> 2 allée Conrad Roentgen                 fax +33 (0)388 602 218
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> <http://cj.sauter.free.fr/xtal>
> 
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