Dear Rohit,

Do you mean that the residues after your "C-terminus" have been deleted because 
there is no convincing electron density for them?
In that case, a charged carboxylate at the N-terminus is incorrect and you 
should delete the OXT atom. Alternatively, you could add one residue at the 
C-terminus and delete all atoms except the N. however, you may still have to 
manually delete the OXT atom.

Best,
Herman

Von: CCP4 bulletin board <[email protected]> Im Auftrag von rohit kumar
Gesendet: Mittwoch, 22. September 2021 23:29
An: [email protected]
Betreff: [ccp4bb] Protein's C-terminal neutral

Hello Everyone,

Is there any way that I could make my protein's C-terminal neutral using Coot?
Actually, I have a protein-peptide complex structure and my peptide is bound at 
the C-terminal end. While making a surface charge diagram it is negatively 
charged (because of the CO group at the end, which is not the end residue of my 
purified protein)  and I want to make it neutral (possibly a peptide bond in 
solution).

Please let me know if I am clear enough with my question.

Thank you

--
Regards
Dr. Rohit Kumar Singh
Postdoctoral fellow
Aurora CO USA



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