Dear all,

Registration is now open for our next industry talk, details and the 
registration link can be found at 
www.ccpbiosim.ac.uk/scivislab21<http://www.ccpbiosim.ac.uk/scivislab21>. The 
talk will take place at 2pm GMT on Friday 26 November 2021 (registration 
deadline 24 November). Anncharlott Berglar from the Scientific Visualisation 
Lab will talk about "Scientific hypothesis-building through visualisation using 
the example of a newly observed phenomenon in COVID-19 patients".

Abstract: Traditionally, scientific visualisation is a method of recording 
scientific data and contents. One step further, visualisation and design 
techniques can complement the scientific method by providing new perspectives 
and by supporting the generation of new ideas. Holding a PhD in biomolecular 
sciences and a MA in scientific illustration, Anncharlott is a freelance 
scientific illustrator and with her knowledge in both fields she aims at 
contributing to the gain of scientific insight in the molecular world.

The Bloch lab recently observed moderate to heavy deformations of red blood 
cells (RBCs) in COVID-19 patients, which we think contribute to the clotting 
events that commonly occur over the course of the disease. The cause or 
mechanism of this observation at a molecular level, however, is unknown. We 
combine classical and state-of-the-art visualisation techniques for 
hypothesis-building, experimental design, and to gain insight into the 
molecular scenery around the RBC membrane when in contact with a SARS-CoV-2 
virus.

Methods such as 3D visualisation, 3D printing and sketching, in combination 
with protein docking and other in-silico experiments allowed building a working 
hypothesis of the mechanism of action underlying the observed RBC deformations. 
Additionally, our approach resulted in communicable and appealing visuals that 
can be used for various purposes and that are able to feature and promote our 
research to the desired target audience.

Best wishes,
Sarah



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