The Williams’ lab at Beckman Research Institute at the City of Hope is looking for a highly motivated X-ray crystallographer to join a dynamic research group (15+) driving translational science to treat patients with cancer and diabetes. The successful candidate will join as a staff scientist and participate in projects that are highly collaborative - often bridging biophysical and synthetic efforts with basic research groups (in vivo and in vitro studies) and practicing clinicians. Critically, City of Hope a large number of core facilities including three FDA-approved GMP facilities to support the translation of these studies to clinical trials. In fact, there are currently has 92 active INDs at City of Hope.
Key Responsibilities: · Involved in multiple projects across the institute including small molecule discovery using fragment screening (diffraction, SPR and DSF based and supported by the synthetic chemistry core) · Will participate in the development of biologics including conditionally activated IO therapeutics. · Immersed in a large group with experience that spans antibody discovery (using cutting edge technologies such as single cell mAb identification), advanced protein engineering and in vivo and in vitro screening with the urgent goal of improving patient’s lives. Basic education, experience and skills required for consideration: · The Staff Scientist must possess a PhD or other doctoral level degree. · Having a background in Structural Biology. · The ideal candidate should also have deep experience running SPR, ITC, CD, AUC and DSF. · Additional experience in CryoEM is desirable. · Experience in cloning and purification of proteins from E coli, yeast, insect and mammalian cell lines is also necessary The lab houses numerous instruments including Rigaku 007 with HiPix detector, Mosquito crystallization robot, Formulatrix Imaging robots, multiple FPLCs, HPLCs, a T200 SPR, Waters Nano ITC, Kinexa3000, Beckman Proteome, Sony Cell sorter, Berkeley Lights Beacon, and ample access to synchrotron time. The Beckman Research Institute and the NCI designated cancer center supports multiple cores. We will be competitive in terms of salary and benefits Please apply at: https://aa067.referrals.selectminds.com/jobs/staff-scientist-protein-purification-and-x-ray-crystallography-8567 Best, John --- John C. Williams, PhD Professor, Dept. of Molecular Medicine; Co-Director, Drug Discovery and Structural Biology Core; Member, Cancer Immunotherapeutics Program, NCI Designated Comprehensive Cancer Center; Beckman Research Institute at City of Hope 1710 Flower Street Duarte CA 91010 Contact: 626 218 1227 (or Ariadna Bello, assistant 626 218 1226 ) ---------------------------------------------------------------------- ------------------------------------------------------------ -SECURITY/CONFIDENTIALITY WARNING- This message and any attachments are intended solely for the individual or entity to which they are addressed. This communication may contain information that is privileged, confidential, or exempt from disclosure under applicable law (e.g., personal health information, research data, financial information). Because this e-mail has been sent without encryption, individuals other than the intended recipient may be able to view the information, forward it to others or tamper with the information without the knowledge or consent of the sender. If you are not the intended recipient, or the employee or person responsible for delivering the message to the intended recipient, any dissemination, distribution or copying of the communication is strictly prohibited. If you received the communication in error, please notify the sender immediately by replying to this message and deleting the message and any accompanying files from your system. If, due to the security risks, you do not wish to receive further communications via e-mail, please reply to this message and inform the sender that you do not wish to receive further e-mail from the sender. (LCP301) ------------------------------------------------------------ ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
