Dear Wu, Just as you say there is an order of magnitude difference in intensity (one is a sealed tube and another is a rotating anode). Our experience with MicroMax007 is that it is often possible to collect a full dataset from a medium-sized crystal overnight. With a sealed tube, this would have been five days which is clearly impractical. The choice is yours, but a system suitable for screening only and a system occasionally capable of full data collection are two different things.
HTH, Sergei Prof. Sergei V. Strelkov Laboratory for Biocrystallography, Department of Pharmaceutical Sciences, KU Leuven O&N2, Campus Gasthuisberg, Herestraat 49 bus 822, 3000 Leuven, Belgium Phone: +32 16 33 08 45, mobile: +32 486 29 41 32, skype sergei.strelkov Lab pages: http://pharm.kuleuven.be/Biocrystallography<http://pharm.kuleuven.be/anafar> From: CCP4 bulletin board <[email protected]> On Behalf Of Wu, Jinhua Sent: Tuesday, January 25, 2022 11:02 PM To: [email protected] Subject: [ccp4bb] Synergy-R vs Synergy-S Dear all, Does anyone have experience on the two new Rigaku systems, Synergy-R and Synergy-S? It seems that Synergy-R has one order of magnitude higher intensity than Synergy-S. But Synergy-S does not need an external water chiller and is maintenance free. Do you think if Synergy-S enough for crystal screening in most cases (nonmembrane proteins)? Anything should be aware of with the two models? Thanks for sharing your thoughts. Best, Jinhua Wu Fox Chase Cancer Center ________________________________ This electronic message is intended to be for the use of the named recipient, and may contain information that is confidential or privileged. This communication may contain protected health information (PHI) that is legally protected from inappropriate disclosure by the Privacy Standards of the Health Insurance Portability and Accountability Act (HIPAA) and relevant Pennsylvania Laws. You can direct questions concerning PHI or HIPAA to the Corporate Compliance and Privacy Officer at (215) 707-5605. If you are not the intended recipient, please note that any dissemination, distribution or copying of this communication is strictly prohibited. If you have received this message in error, you should notify the sender immediately by telephone or by return e-mail and delete and destroy all copies of this message. ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
