Dear all,

I wanted to call your attention to an exciting job opportunity that integrates 
cryoEM and membrane biophysics to understand how the immune system fights 
infection. The position is funded by a Wellcome Trust Investigator Award in the 
labs of Doryen Bubeck (Imperial College London) and Mark Wallace (Kings College 
London). Please see below for details on the position and how to apply.

Best wishes,

Doryen Bubeck

_________________________________

Dr. Doryen Bubeck
Director Centre for Structural Biology
Department of Life Sciences
Imperial College London

https://www.imperial.ac.uk/people/d.bubeck
@bubecklab


Job Summary

The Bubeck laboratory (https://www.imperial.ac.uk/people/d.bubeck) is looking 
to recruit a Research Associate with high level of expertise in cellular 
tomography. Additional expertise in microbiology is very suited for the 
position.

Duties and responsibilities

This post, funded by a highly competitive Wellcome Trust Investigator Award, 
aims to uncover how the membrane attack complex (MAC) kills bacterial 
pathogens. The project’s primary objective is to discover 1) where MAC is 
located within the bacterial envelope and 2) how does MAC activation control 
bacterial killing. You will join an exciting interdisciplinary team of 
structural biologists and membrane biophysicists to tackle a major question in 
understanding host-pathogen interactions. The project focuses on cryo electron 
tomography-based studies of MAC within the context of a series of model 
membrane systems. The research builds on the lab’s strong track-record in 
complement structural biology and is closely linked with research activities in 
membrane biophysics with Prof. Mark Wallace 
<https://www.kcl.ac.uk/research/wallace> at King’s College London.

Essential requirements

You will have a PhD (or be near completion of) in structural biology, ideally 
with experience in cellular tomography. You must have a strong research track 
record in studying protein-protein and protein-membrane complexes preferably 
demonstrated by first author publications in international journals. Experience 
in the design and execution of workflow for structure determination of proteins 
or cellular systems from sample preparation to acquisition and analysis of 
structural biology data.

You must have excellent verbal and written communication skills, and be able to 
write clearly and succinctly for publication. You must also be able to relate 
well with others, form positive relationships with a wide range of people and 
to work as part of a team, as well as independently. The ability to develop and 
apply new concepts and have a creative approach to problem-solving, to set and 
attain research objectives in a multidisciplinary team are also essential.

Further Information

This is a full-time, fixed-term appointment available for up to three years, 
with the possibility of extension. You will be based at South Kensington Campus.

Candidates who have not yet been officially awarded their PhD will be appointed 
as Research Assistant within the salary range, £36,694- £39,888 per annum.

Informal enquiries to Dr. Doryen Bubeck: 
d.bub...@imperial.ac.uk<http://imperial.ac.uk/>

Closing date is 30 March 2022.

To apply 
https://www.imperial.ac.uk/jobs/description/NAT01088/research-associate-structural-biology

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