Dear colleagues, my group is looking to hire a motivated postdoc with experience in cell biology, a keen interest in proteomics, and the ability to communicate with structural biologists. It would be fantastic if you could forward the ad below to suitable candidates and/or circulate it within your institutes.
Many thanks for your help and best wishes, Sonja Lorenz Independent Group Leader Ubiquitin Signaling Specificity Max Planck Institute for Multidisciplinary Sciences Am Fassberg 11 37077 Goettingen Germany —————————————————————————————————————— Max Planck Institute for Multidisciplinary Sciences, Göttingen/Germany The Max Planck Institute for Multidisciplinary Sciences in Göttingen is an internationally leading research institute of exceptional scientific breadth. The largest institute of the Max Planck Society, it comprises more than 40 research groups and employs around 1,000 people from over 50 nations. The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites applications for a position as Postdoc (f/m/d) – Cell biology of ubiquitin ligase complexes – Our lab aims to understand how ubiquitin − a single, small protein − achieves specificity in regulating virtually all aspects of eukaryotic cell biology. A major key lies in the action of ubiquitin ligases, the most diversified class of enzymes of the ubiquitin system. The immense potential of ubiquitin ligases as therapeutic targets is illustrated by the clinical efficacy of thalidomide and derivatives in the treatment of hematologic malignancies. However, progress towards rationally manipulating these enzymes has been impeded largely by our insufficient understanding of their integration into macromolecular complexes and the associated structural and functional consequences. We aim to identify and characterize macromolecular complexes of ubiquitin ligases to decipher the molecular basis of their specificities in substrate recognition and ubiquitin chain formation. To this end, we combine chemical-biological, biochemical, cell biological, and structural approaches with a particular focus on cryo-electron microscopy. We have a fully-funded postdoc position available for a talented individual to uncover cellular ubiquitin ligase assemblies implicated in neurodevelopmental disorders. Your profile: You have a PhD or equivalent degree in a relevant subject area, such as cell and molecular biology, biochemistry or biomedicine. You have a proven track record in molecular cloning and cell biology, specifically in one or more of the following techniques: Crispr/Cas9-mediated gene editing, RNA interference, cell fractionation, co-IP, immunofluorescence, and live-cell imaging. Additional experience in neuronal cell culture and/or proteomics will be beneficial. You are curiosity-driven and eager to interact with biochemists and structural biologists. You are passionate about science and keen to establish creative new approaches to tackle challenging protein complexes. You are self-motivated and independent, and enjoy being part of an international, multidisciplinary team. About us: We are an independent research group at the Max Planck Institute for Multidisciplinary Sciences, one of Germany’s premier research campuses with leading-edge infracture in all fields of structural and cell biology. We are a highly international and interdisciplinary team, funded by the Max Planck Society, the German Research foundation, and the EMBO YIP. The historic city of Goettingen, located in the center of Germany, offers great outdoor and cultural opportunities, a bustling student scene, and an impressive scientific heritage. Position details: The position should be filled as soon as possible, but the exact start date is flexible. The position is initially for 2 years with the possibility of extension. Payment and benefits are based on the TVöD guidelines. The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds. Application: Please submit your application including cover letter (explaining background and motivation), CV, transcripts, and publication record by e-mail as a single PDF file to the email address below. Review of applications will begin immediate. Informal inquiries are also welcome. ausschreibung26...@mpibpc.mpg.de <mailto:ausschreibung26...@mpibpc.mpg.de> Max Planck Institute for Multidisciplinary Sciences Research Group „Ubiquitin Signaling Specificity“ Dr. Sonja Lorenz Am Fassberg 11 37077 Göttingen Germany Twitter @SLorenzLab Lab Homepage: https://www.mpinat.mpg.de/lorenz <https://www.mpinat.mpg.de/lorenz> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
