Dear all,

Could I draw your attention to a great position that we have available to join 
a two year, MRC DPFS-funded project to provide structural and biophysical input 
to a drug discovery project in the CRUK Newcastle Drug Discovery Unit.

The project is pursuing an exciting structural hypothesis to develop therapies 
to address an unmet need for treatments for patients with ovarian cancer.  It 
is currently in early lead optimisation, and the post holder will be joining a 
well founded team to develop and apply techniques of structural biology 
(crystallography/cryo EM), biophysics (SPR/ITC), and cellular and cell-free 
assays to progress the project towards clinical candidate selection.

Because the work will be conducted in a group that has been instrumental in the 
development of licensed drugs, this post will offer the holder an insight into 
authentic and effective modern structure based drug discovery.  It would 
especially suit someone looking to round off their structural biology skills 
with a view to pursuing careers in academic or industrial drug discovery.

Informal approaches can be made directly to myself 
([email protected]<mailto:[email protected]>) or Jane 
Endicott ([email protected]<mailto:[email protected]>), 
but anyone considering the position should apply through the Newcastle 
University portal using the URL:

https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate/778968301/

This link also offers further particulars for the post, for which the closing 
date is 22nd April.

With best wishes,

Martin




Martin Noble
Professor of Structural Biology and Anticancer Drug Design
Translational and Clinical Research Institute
Faculty of Medical Sciences
Newcastle University
Paul O’Gorman Building
The Medical School
Framlington Place
Newcastle Upon Tyne
NE2 4HH

Tel: (+44) 191 2084466
E-mail: [email protected]<mailto:[email protected]>
Drug discovery: http://research.ncl.ac.uk/drugdiscovery
Cell cycle research: http://research.ncl.ac.uk/cellcyclestructuralbiology

[cid:[email protected]][cid:[email protected]]


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