Hi All, I would like to draw your attention to the following open position at CHARM Therapeutics located in Cambridge, UK.
Many thanks, Dr Andy Dore ****** For those that are interested, the application portal link is below: https://s101.recruiting.eu.greenhouse.io/plans/4027860101 ****** JOB DESCRIPTION Scientist, Biochemistry CHARM Therapeutics is a biotech company focused on delivering transformational medicines that will address difficult-to-drug targets in key oncogenic pathways. CHARM has developed the first highly accurate, high throughput protein-ligand co-folding algorithm (DragonFold), driven by end-to-end 3D deep learning. Our platform enables the rapid generation of highly differentiated clinical candidates, and our ambition is to revolutionise drug discovery. CHARM Therapeutics is establishing a state-of-the-art R&D facility in Cambridge, UK. We are currently seeking a motivated Biochemist to join the Structural Sciences group at CHARM Therapeutics. The position is within a lab-based team, working on high throughput crystallographic and CryoEM structural targets to fully enable and drive multiple SBDD / Med Chem campaigns. The successful candidate will join a multidisciplinary, highly collaborative discovery team to invent novel medicines and drive them towards the clinic. Role Requirements: The successful candidate will be expected to meet the following criteria: A degree in biochemistry / molecular biology, or a related discipline, is required. Experience in a biotech/pharma setting may be advantageous. Molecular biology / cloning / protein engineering skills and knowledgeable in expression construct design, and downstream purification strategies. Demonstrable experience in the expression and purification of target proteins from recombinant systems (both bacterial and eukaryotic advantageous) utilising various affinity systems. Experience in the use of FPLC systems and different approaches to purify recombinant target proteins to homogeneity. Knowledgeable in the application of protein biochemistry to aspects of drug discovery programs including structural biology and biophysical analyses Excellent organisational / interpersonal skills with the ability to work as part of a team. What is on Offer: The chance to work in a highly collaborative, progressive and intellectually stimulating environment, applying state of the art AI-based techniques to revolutionise drug discovery. Competitive base salaries along with regular appraisals and reviews. Share options in CHARM Therapeutics through the EMI scheme. Private Healthcare, including dental and optical. Gym membership. Budget for employee development; training courses and conferences. Fruit and snacks delivered to our offices. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/