We don’t have any computers with Apple silicon in our group yet to test Phaser 
on ourselves. When preparing the Phenix distribution, Billy Poon has run tests 
and when Phaser is compiled for Intel and run through Rosetta 2, it’s generally 
faster than on a recent Intel Mac. However, there have been reports from Phenix 
users of severe slowdowns, and we don’t understand what the special 
circumstances are that cause it to slow down on specific jobs.

The best performance is when it’s compiled natively for the M1 processor, and I 
believe both Phenix and CCP4 are aiming to distribute natively-compiled 
software as soon as technical complications are worked out. So hopefully this 
is just temporary!

I hadn’t realised that the OpenMP wasn’t enabled on CCP4. In Phenix, there were 
issues preventing the use of OpenMP with Python2, but those should go away when 
the Python3 version is ready to deploy.

Best wishes,

Randy Read

> On 28 Jun 2022, at 16:45, Lau Kelvin 
> <[email protected]> wrote:
> 
> Hello
> 
> I have noticed running normal programs like Phaser MR on a MacBook Pro 
> (M1Pro) that jobs are extremely slow compared to my older computers.
> 
> It doesn’t seem to be running over multiple CPUs anymore.
> 
> Has this also been seen by others?
> 
> Best
> 
> Kelvin
> 
> 
> -- 
> Kelvin Lau
> Protein production and structure core facility - PTPSP
> EPFL SV PTECH PTPSP 
> AI 2146 (Bâtiment AI) 
> Station 19 
> CH-1015 Lausanne
> Switzerland
> Email: [email protected]
> Phone: +41 21 69 34494
> 
> 
> To unsubscribe from the CCP4BB list, click the following link:
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> 

-----
Randy J. Read
Department of Haematology, University of Cambridge
Cambridge Institute for Medical Research     Tel: +44 1223 336500
The Keith Peters Building                               Fax: +44 1223 336827
Hills Road                                                       E-mail: 
[email protected]
Cambridge CB2 0XY, U.K.                              
www-structmed.cimr.cam.ac.uk


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