Dear all,

Could I draw your attention to a great position that wehave available to join a 
two year, MRC DPFS-funded project to providestructural and biophysical input to 
a drug discovery project in the CRUKNewcastle Drug Discovery Unit.

The project is pursuing an exciting structural hypothesisto develop therapies 
to address an unmet need for treatments for patients withovarian cancer. It is 
currently in early lead optimisation, and the post holderwill be joining a 
well-founded team to develop and apply techniques ofstructural biology 
(crystallography/cryo-EM), biophysics (SPR/ITC), andcellular and cell-free 
assays to progress the project towards clinicalcandidate selection.

Because the work will be conducted in a group that hasbeen instrumental in the 
development of licensed drugs, this post will offerthe holder an insight into 
authentic and effective modern structure based drugdiscovery.  It would 
especially suitsomeone looking to round off their structural biology skills 
with a view topursuing careers in academic or industrial drug discovery.

Informal approaches can be made directly to Martin 
Noble([email protected])or Jane Endicott 
([email protected]),but anyone considering the position should 
apply through the Newcastle Universityportal using the URL:

https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate/839154501/

This link also offers further particulars for the post,for which the closing 
date is 8th September 2022.

Best wishes,

Mat

 

Dr Mathew Martin
Cancer Research UK Newcastle Drug Discovery UnitTranslational and Clinical 
Research Institute Discovery of Medicines PaulO'Gorman Building Medical 
SchoolNewcastle University Framlington Place Newcastle upon TyneNE2 4HHEmail: 
[email protected] Newcastle DDU - Cancer Research UK Newcastle Drug 
Discovery Unit | Cancer Research UK Newcastle Drug Discovery Unit | Newcastle 
University



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