Dear colleagues,
my research group has exciting openings for a PhD student or postdocs to
explore molecular mechanisms in the ubiquitin system.
We are particularly looking to recruit candidates with a background and
interest in protein biochemistry and X-ray crystallography or cryo-EM. Please
find the ad below or via the following link:
https://www.mpinat.mpg.de/4152583/34-22?c=3895698
<https://www.mpinat.mpg.de/4152583/34-22?c=3895698>
I would be grateful if you could make this opportunity available to suitable
candidates.
Many thanks and best wishes,
Sonja Lorenz
==============================================
The Max Planck Institute for Multidisciplinary Sciences is a leading
international research institute of exceptional scientific breadth. With more
than 40 research groups and some 1,000 employees from over 50 nations, it is
the largest institute of the Max Planck Society.
The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites
applications for positions as
PhD student or Postdoc (f/m/d)/
– Specificity mechanisms in the ubiquitin system –
Our lab aims to understand how the protein modifier ubiquitin achieves
specificity in regulating virtually all aspects of eukaryotic homeostasis. A
major key lies in the action of ubiquitin ligases, the most diversified class
of enzymes in the ubiquitin system with powerful therapeutic potential.
However, progress towards rationally manipulating these enzymes has been
impeded largely by our insufficient understanding of their conformational
dynamics, macromolecular interactions, and functional integration into cellular
pathways. We offer fully-funded PhD student or postdoc positions to explore
different aspects of specificity in ubiquitination: (i) the macromolecular
network of ubiquitin ligases in the cell and associated functions; (ii) the
cross-talk of ubiquitination with other posttranslational modifications, such
as phosphorylation and redox-dependent modifications; (iii) the structural
mechanisms of ligases at the ribosome. Exciting projects with either structural
or biochemical or cell biological focus are available and will be tailored to
the interests and expertise of the successful candidates.
PhD candidates should hold/soon expect a MSc or equivalent degree in a relevant
area of the life sciences and have initial experience in one or more of the
following techniques: protein biochemistry, cell biology, chemical biology, or
any aspect of structural biology.
Postdoctoral candidates should hold/soon expect a PhD or equivalent degree in a
relevant area of the life sciences and have a proven track record in one or
more of the following techniques: cryo-EM, X-ray crystallography,
isolation/reconstitution of protein complexes, or cell biology (e.g.,
Crispr/Cas9-mediated gene editing, RNA interference, co-IP or IF). Additional
experience or interest in mass spectrometry/proteomics will be beneficial.
Candidates for either position should be curiosity-driven, self-motivated,
passionate about science, and eager to work in an international,
multi-disciplinary team.
We offer:
· competitive research in an inspiring, world-class environment
• professional training, networking and career-development
opportunities; free language courses
· on-site health management: free fitness and yoga room, sports groups,
beach volleyball league, and courses for a "moving lunch break”
• a wide range of opportunities to balance work and family life,
including an on-campus kindergarten and vacation care
• spacious on-site cafeteria with diverse meals; espresso bar
· initiatives for sustainability and a green environment with an on-site
biotope
About us:
Based at one of Germany’s premier research campuses, our research group has
access to leading-edge infrastructure in all areas of cell and structural
biology, including cryo-EM. We are an international team, supported by the Max
Planck Society, the German Research Foundation, and the EMBO Young Investigator
Program. Our working language is English; knowledge of German is not required.
The historic city of Göttingen, located in the center of Germany, offers great
outdoor and cultural opportunities, a vibrant student scene, and an impressive
scientific heritage.
Position details:
The positions should be filled as soon as possible; the exact start date is
flexible. PhD students will be funded for three years (with a possibility of
extension) and have the opportunity to enroll in one of several PhD programs in
collaboration with the University of Göttingen. Postdoc positions are initially
funded for two years with a possibility of extension. Payment and benefits are
based on the TVöD (wage agreement for public service personal) guidelines.
The Max Planck Society is committed to increasing the number of individuals
with disabilities in its workforce and encourages applications from such
qualified individuals. The Max Planck Society strives for gender and diversity
equality. We welcome applications from all backgrounds.
Application:
Please submit your application including a cover letter (explaining background
and motivation), CV, academic transcripts, publication list, and the contact
addresses of 3 references as a single PDF file to the email address below.
Review of applications will begin immediately.
[email protected] <mailto:[email protected]>
Max Planck Institute for Multidisciplinary Sciences
Research Group „Ubiquitin Signaling Specificity“
Sonja Lorenz
Am Faßberg 11
37077 Göttingen
Germany
Web: https://www.mpinat.mpg.de/lorenz <https://www.mpinat.mpg.de/lorenz>
Twitter: SLorenzLab
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