Hi everyone, The deadline to submit a screening proposal to the LCLS XFEL has been extended! For delicate crystals and/or for crystals available in lower quantities, the standard goniometer setup at LCLS-MFX is a useful option available to all general users applying for beamtime.
See below for more information on how to apply. _______________________________________________ We are pleased to announce the next call for LCLS Protein Crystal Screening (PCS) Proposals. LCLS is seeking proposals for PCS beamtime to be awarded during LCLS Run 21 expected to be scheduled between October 2022 and June 2023. The LCLS Protein Crystal Screening (PCS) program aims to enable increased access to LCLS beamtime for biological structure determination by making use of short, 6-12 hour runs to screen the quality of different sample preparations or potentially collect a full data set under good running conditions. To enable measurements within such a short time frame and maximize efficiency and the chances of success, these studies must be carried out with limited instrumentation flexibility to minimize the time impact of setup changes. PCS experiments at atmospheric pressure are expected to be available at the *MFX* <https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Flcls.slac.stanford.edu%2Finstruments%2Fmfx&data=05%7C01%7Cguc9%40pitt.edu%7Cd7c0da2dc0c24dc4be6a08daa00bbb4e%7C9ef9f489e0a04eeb87cc3a526112fd0d%7C1%7C0%7C637998269504216583%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=YEXrdFwdqqPVqyfUTIBF441POiDe7n1lnrwfiyGMWMw%3D&reserved=0> instrument with multiple options likely to be available, including a fixed target system, a Droplet-on-Demand system, and a liquid jet system compatible with various types of jets. The following sample delivery configurations (at the discretion of LCLS) are expected to be supported at MFX (in atmosphere) for PCS in this current call for proposals: - Gas Dynamic Virtual Nozzle (GDVN) - Dual Flow Focusing Nozzles (DFFN) - Lipidic Cubic Phase (LCP) jets - Microfluidic Electrokinetic Sample Holder (MESH) - Droplet-on-Demand (DoD) - Sheet Jets Other sample delivery techniques supplied by user groups (i.e., liquid jet, fixed target, goniometer, tape drive, etc.) that are compatible with the basic MFX system could also be considered if the schedule allows it and at the discretion of LCLS. > For full details of the call, please visit > *https://lcls.slac.stanford.edu/proposals/run21-pcs <https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Flcls.slac.stanford.edu%2Fproposals%2Frun21-pcs&data=05%7C01%7Cguc9%40pitt.edu%7Cd7c0da2dc0c24dc4be6a08daa00bbb4e%7C9ef9f489e0a04eeb87cc3a526112fd0d%7C1%7C0%7C637998269504216583%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=0bYmamR6wvnfvd6CabGOR6ebYp9omk7VdHdaZNovcew%3D&reserved=0>* Questions about the LCLS PCS program should be directed to *Christopher Kupitz* (*ckup...@slac.stanford.edu <ckup...@slac.stanford.edu>*). For more general information about LCLS, please visit: *http://lcls.slac.stanford.edu* <https://nam12.safelinks.protection.outlook.com/?url=http%3A%2F%2Flcls.slac.stanford.edu%2F&data=05%7C01%7Cguc9%40pitt.edu%7Cd7c0da2dc0c24dc4be6a08daa00bbb4e%7C9ef9f489e0a04eeb87cc3a526112fd0d%7C1%7C0%7C637998269504216583%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=SeHt0eDvpD6scT0LX508HMs6%2Bf1J%2BJHaTA2jehV2quk%3D&reserved=0> -- Art Lyubimov, PhD Staff Scientist SSRL SMB Crystallography 2525 Sand Hill Road mail stop 99 Menlo Park, CA 94025-7015 (415) 325-2057 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
