*PhD Position: molecular structural biology of mechano-signalling cascades in 
muscle *

We have a vacancy for a PhD student to join our laboratory at the Department of 
Biology, University of Konstanz, Germany.

Our laboratory studies the molecular mechanisms underpinning the architecture, 
stress response, adaptation and disease process of striated muscle. The focus 
of this PhD project will be on identifying protein components that mediate the 
communication of the contractile sarcomere with other cellular organelles in 
function of mechanical activity. We apply an integrative approach to structural 
biology that combines a rich variety of biochemical, biophysical, computational 
and structural methodologies, with emphasis on X-ray crystallography.

Qualifications

Applicants should hold (or be in the process of acquiring) a Master's degree in 
biophysics, biochemistry or related discipline, and be interested in learning 
both laboratory-based and computational methods as applicable to the study of 
biomolecules. A strong motivation to understand and discover the molecular 
mechanisms that enable function in living cells is required. Basic experience 
in molecular biology and/or recombinant protein production is expected. Good 
command of written and spoken English, the ability to work in a team, and good 
communication and organizational skills are required. Some initial knowledge of 
a structural/biophysical method would be of advantage. 

Application

Applications should contain the following documents in PDF format: 

1. Applicant's CV
2. Copies of original degree transcripts displaying marks obtained
2. A statement of motivation for pursuing PhD studies in molecular sciences 
3. Contact details of two referees

Informal enquiries and application materials should be submitted by email to:

olga.may...@uni-konstanz.de

The position is available from January.2023 (or to be filled as soon as 
possible thereafter). 

===================================
Prof. Olga Mayans
Biophysics and Structural Biology
Dept of Biology 
University of Konstanz
D-78457 Konstanz, 
Germany 
Tel: +49 7531 88-2212

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