Dear CCP4,

I apologize if this is off topic but I thought this may be a good community to 
ask. Before we re-invent the wheel this end, we are looking for any commercial 
source of three-dimensional macromolecular models that can be used to teach how 
drugs are designed to fit to protein targets. Our audience is mid to advanced 
high-school students and we are looking for materials that can withstand being 
passed around the students and can teach basic concepts of how structure can 
inform ligand binding.

There are commercial sources of these models for macromolecules that we are 
aware of, but few if any that allow us to manipulate a drug and show how it 
fits to the model. We would love to find ones where a student may have name 
recognition of the drug concerned and we can show how it would fit to the 
target of that drug.

Any experience in this area and a source of such models would be greatly 
appreciated. We enjoy our interactions with these students and have the 
advantage of a professional high-school science teacher/science curriculum 
developer on staff with Nicole Terranova (copied on the email). Our program 
related to this is being developed and if anyone has any experiences with this 
nature of teaching, any offline feedback would be appreciated.

Thank you,

Eddie

Edward Snell Ph.D.

President and CEO | Hauptman-Woodward Medical Research Institute
Director | NSF BioXFEL Science and Technology Center
Professor, Materials Design and Innovation | University at Buffalo, SUNY
Fellow of the American Crystallographic Association - The Structural Science 
Society

p: +1 716 898 8631 | f: +1 716 898 8660
e: [email protected]<mailto:[email protected]>
skype: eddie.snell

Hauptman-Woodward Medical Research Institute
700 Ellicott Street | Buffalo, NY 14203-1102
hwi.buffalo.edu<https://hwi.buffalo.edu/>


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