The Nucleic Acid Knowledgebase (nakb.org https://nakb.org/) is a new web-based 
data resource for experimentally-determined structures containing DNA and RNA 
nucleic acid polymers and their biological assemblies.

NAKB currently indexes 16,000+ nucleic acid-containing structures derived from 
all major structure determination methods (X-ray, NMR, and cryo-electron 
microscopy), including all held by the Protein Data Bank (PDB), and 48 
structures held only by the Nucleic Acid Database (NDB). The resource is 
updated weekly on Thursdays at noon, US Eastern time.

As the planned successor to NDB (see Berman, Lawson & Schneider (2022), 
Developing Community Resources for Nucleic Acid Structures. Life 12, 540, 
https://doi.org/10.3390/life12040540 https://doi.org/10.3390/life12040540), 
NAKB preserves all of the functionality of the legacy service, including 
search, tabular reports, statistics, 2D and 3D visualization tools, education 
and standards pages, and a nucleic-acid community web and software resource 
list.

For each structure, core descriptive information gathered from PDB or NDB is 
integrated with annotations curated by NDB/NAKB and nucleic-acid centered 
external resources including RNACentral, Rfam, DNATCO, OnQuadro, 3DFootprint, 
DNAproDB, and BGSU RNA equivalence classes. NAKB also provides interactive 
tables of nucleotide, base-pair, and base-pair step parameters (DSSR), 2D 
folding diagrams (RNAView, R2DT), and a 3D viewer (Mol*).

The legacy NDB website, ndbserver.rutgers.edu http://ndbserver.rutgers.edu/, 
will be retired in early July 2023. At that time, all NDB web traffic will 
forward to https://nakb.org https://nakb.org/. All links to individual entry 
NDB atlas pages will automatically redirect to NAKB atlas pages.

NAKB development is funded by National Institutes of Health R01GM085328. NDB 
has been funded in the past by the National Science Foundation and the 
Department of Energy.

Questions/comments are welcome. You can reply to this post or send to 
[email protected] or [email protected]

Cathy Lawson
Research Collaboratory for Structural Bioinformatics
Institute for Quantitative Biomedicine
Rutgers University

original pdb-l post:
https://lists.wwpdb.org/empathy/thread/R72VOXINMIBGKVXY3B22IIPY5RTUE63V

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