Greetings to all.

I am trying to dock a co crystallized ligand using GLIDE. The co
crystallized ligand is a big molecule with multiple rotatable bonds. GLIDE
is unable to regenerate the ligand pose. I tried limiting the rotatable
bonds, but in vain. I would be grateful to receive any advice or suggestion
as to how I can proceed.

Thanking you in advance,
Regards,
Thripthi S.

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