Dear colleagues,

A fully funded PhD position is available in the newly established Rengachari 
lab, within the Section for Structural and Synthetic Biology at Imperial 
College London. The position is open to UK/Home students with a strong 
background in the life sciences.

Our lab studies the molecular mechanisms of RNA polymerase II transcription, 
with a particular interest in how these processes influence genome maintenance 
and how viral infection interrupts these mechanisms. We aim to understand how 
these pathways become dysregulated in infection, neurodegenerative disease, and 
cancer. For more information on our research and approach, refer to our recent 
work on transcription initiation and termination (Rengachari et al., 2024, Nat. 
Struct. Mol. Biol.; Rengachari et al., 2022, Nat. Struct. Mol. Biol.; 
Rengachari et al., 2021, Nature).

What we offer
   
   -    
The opportunity to join a new and growing lab, with close mentorship and the 
chance to shape the group’s culture.

   -    
Training in cutting‑edge structural biology methods (cryo‑EM, biochemistry, and 
complementary approaches).

   -    
A collaborative environment within the Section for Structural and Synthetic 
Biology and the Department of Infectious Disease, with strong links across 
Imperial and international partners.

   -    
A project designed to build on your existing skills while giving you scope to 
grow into an independent researcher.


Candidate profile
   
   -    
Degree in life sciences (molecular biology, biochemistry, structural biology, 
or related fields).

   -    
Enthusiasm for mechanistic questions in gene expression, genome biology, and 
host–pathogen interactions.

   -    
Motivation to work collaboratively and contribute to a supportive lab culture.



How to apply 

Interested candidates should send a CV, a short statement of research 
interests, and the names of at least two referees to 
[email protected]. Informal enquiries are welcome. Overseas 
candidates interested in applying for external fellowships are also encouraged 
to get in touch.


Best wishes, 
Srinivasan


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