Dear All,

we test BET by gel clot method.

I had a query for one of the tests. We received from one of our partners
Clindamycin Injection 150mg/ml for BET testing. The LImit in Indian
pharmacopoeia is stated as 6 EU/ml.

As per the Pharmacopoeia we have to dilute the Injection with LRW to obtain
solution of 10mg/ml prior to testing. So substituting that in equation for
MVD we obtain the value of 480 as MVD (sensitivity of lysate is 0.125 Eu/ml)

However the vendor uses the potency of product as 1ml/ml and hence MVD for
them is 48.

Can you please clarify which is the correct way for testing this product.

Any assistance is appreciated.

Megha Goyal

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