Postdoctoral Fellows in AI and Computational Biology — National University of 
Singapore

 

The Yang Zhang Lab at the National University of Singapore (NUS) is recruiting 
two postdoctoral fellows in artificial intelligence and computational biology. 
The lab is jointly based in the School of Computing, the Yong Loo Lin School of 
Medicine, and the Cancer Science Institute of Singapore, and operates at the 
interface of computer science, structural biology, and biomedical research. 
This recruitment reflects the ongoing expansion of the lab’s AI-for-Science 
research program.

 

These positions target the development of next-generation AI methods for 
biomolecular modeling and AI-driven drug discovery, with a focus on protein and 
RNA folding, structure prediction, and sequence design. The research centers on 
building foundation-model architectures that integrate sequence, structural, 
and physical information to model functionally relevant biomolecular states and 
interactions. The work is explicitly method-driven, emphasizing original 
algorithm and model development that advances the state of the art, rather than 
the application of existing tools or pipelines to standard benchmarks.

 

The Zhang Lab provides a research environment designed to support large-scale, 
method-driven AI development in molecular and biomedical science. Postdoctoral 
fellows will work in a computationally intensive setting with access to 
large-scale HPC systems, including hybrid NVIDIA GPU/CPU clusters, and are 
expected to carry projects from algorithmic conception through large-scale 
training and rigorous evaluation. The lab is embedded in a strong 
interdisciplinary ecosystem at NUS, with close proximity to experimental and 
clinical collaborators when scientifically relevant. Positions are based in 
Singapore, an international, English-speaking research hub offering excellent 
connectivity, stability, and quality of life. The lab provides an 
internationally competitive salary and benefits package, together with strong 
logistical and research support.

 

Applicants should hold, or be close to completing, a PhD in computer science, 
machine learning, biophysics, or a closely related field. We seek candidates 
with solid programming skills and the ability to develop new models or methods. 
As postdoctoral fellows are expected to independently lead research projects, 
candidates should demonstrate the ability to define research directions, take 
ownership of their projects, and drive them to completion. A strong publication 
record in relevant venues is expected. Experience in structural bioinformatics 
or large-scale deep learning is a plus, but the primary criterion remains 
methodological depth and research creativity.

 

To apply, please submit a single PDF to Prof. Yang Zhang ([email protected]) 
containing a curriculum vitae with a full publication list, a concise research 
statement outlining prior work and future research plans, and contact 
information for three referees. Review of applications will begin immediately 
and continue until the positions are filled. Start dates are flexible. More 
information about the Zhang Lab and Prof. Yang Zhang’s research can be found at 
https://zhanggroup.org and 
https://scholar.google.com/citations?user=MtBs-kMAAAAJ.

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