Postdoctoral Fellow / Research Associate – Structural Biology & DNP-Enhanced Crystallography Crystallization Lab, Meharry Medical College, Nashville, TN
The Crystallization Lab at Meharry Medical College seeks a Postdoctoral Fellow or Research Associate to join a collaborative, multi-institutional project developing paramagnetic sample preparation protocols for Dynamic Nuclear Polarization (DNP)-enhanced structural analysis of protein crystals. The successful candidate will work under the direction of established investigators in Nashville and at Oak Ridge National Labs. Responsibilities include: * Developing and optimizing protocols for incorporating paramagnetic reagents (e.g., TEMPO-based radicals) into protein crystals via soaking, co-crystallization, and site-specific labeling strategies * Protein expression, purification, and crystallization of model systems and biomedically relevant targets * X-ray diffraction screening and data collection, including remote access at SSRL * Mentoring undergraduate and graduate student trainees Qualifications * Ph.D. in structural biology, biochemistry, biophysics, or a related field (postdoc) or M.S./Ph.D. with relevant experience (research associate) * Hands-on experience with protein crystallography, including crystal growth and optimization * Experience with protein expression and purification (bacterial and/or eukaryotic systems) * Familiarity with X-ray diffraction data collection and processing (CCP4 suite, PHENIX, or equivalent) * Strong organizational skills and ability to work across multiple collaborative teams Preferred * Experience with paramagnetic reagents, fragment soaking, or related crystal manipulation techniques * Familiarity with DNP-NMR, EPR, or solid-state NMR methods * Interest in or experience with training/mentoring students * Experience with automated or remote synchrotron data collection To Apply Send cover letter, CV and contact information for three references to Jamaine Davis at [email protected]<mailto:[email protected]> and Minu Chaudhuri ([email protected]<mailto:[email protected]>). Review of applications will begin immediately and continue until the position is filled. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
