Greetings to all, I am currently working on understanding the structure-based sequence alignment of the crystal structure of NOXA BH3 domain and the complete protein structure obtained from AlphaFold. According to my understanding, the BH3 binding domain from the crystal structure should get aligned with the BH3 domain in the entire protein structure. However, this is not the case and the identical amino acids of the BH3 domains are not getting aligned. I would be grateful to know if this is a correct approach to proceed with the structure based protein alignment.
Thanking you in advance With regards, Thripthi S. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
