Dear all,

I had sent the below message to the Bruker mailing list, but much to my
surprise not a single answer. Maybe the ccp4bb has some information
about how to compute an ESP from a CIF (small molecule, not mmCIF),
taking symmetry into account?

For one of our recent papers, we used a next-neighbours composition,
which worked fine, but may not be as accurate as taking symmetry
properly into account. 

Best wishes,
Tim


Begin forwarded message:

Date: Mon, 22 Jun 2026 14:09:00 +0200
From: Tim Gruene <[email protected]>
To: bruker-group <[email protected]>
Subject: walkthrough ESP from CIF


Dear all,

apparently some programs can compute electrostatic potentials taking
crystallographic symmetry into account (nespresso, vasp, cp2k et al?).

I have been trying to understand documentations, with and without AI,
but so far no good. The documentation of above programs seem to have
the prerequisite of understanding the terms of theoretical chemistry,
which is not the case for me.

Could anyone share a walk-through how to 
- start from a (small-molecule, not mm-) CIF file, 
- produce a file containing a desciption of the ESP (within asymmetric
  unit, unit cell, user-input volume) with boundary conditions imposed
  by the crystallgraphic spacegroup.
- display the map on screen

For the latter, I have used VMD, but VMD does not speak symmetry and
e.g. shows black when outside the unit cell, so the input file would
need to cover the volume I am interested in.

I hope such walk-through exist and would greatly appreciate a pointer.

Best wishes,
Tim


-- 
--
Tim Gruene
Head of the Core Facility Crystal Structure Analysis
Faculty of Chemistry
University of Vienna

Phone: +43-1-4277-70202

https://ccsa.univie.ac.at

GPG Key ID = A46BEE1A

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-- 
--
Tim Gruene
Head of the Core Facility Crystal Structure Analysis
Faculty of Chemistry
University of Vienna

Phone: +43-1-4277-70202

https://ccsa.univie.ac.at

GPG Key ID = A46BEE1A

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