There is a paper on this...

https://journals.iucr.org/j/issues/2025/02/00/gj5316/index.html

On Thu, Jul 2, 2026 at 8:57 AM Martin Hu <
[email protected]> wrote:

> Dear all,
>
> I would like to ask for some advice on the best way to handle poorly
> defined side chains for deposition of a low-resolution (~3.6 Å) X-ray
> structure.
>
> For a number of residues in my structure, there is little or no side-chain
> density, so I do not feel confident modelling the full side chains. At the
> moment, I have deleted the residues that are not supported by the electron
> density, which also gives better geometry and refinement statistics.
>
> I asked the PDBe deposition team whether they had any preference between
> deleting the unsupported side-chain atoms or keeping them with zero
> occupancy. They replied that they do not have any specific requirements, as
> long as the deposited model is appropriate.
>
> I was therefore wondering how people here would normally deal with this
> situation for PDB deposition. Would you generally:
>
> * delete the unsupported side-chain atoms,
> * keep the full side chains but set the unsupported atoms to zero
> occupancy,
> * or use another approach?
>
> I’d be interested to hear what people usually do for structures around
> this resolution.
>
> Many thanks in advance.
>
> Best regards,
>
> Martin Hu
>
> ########################################################################
>
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1
>
> This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a
> mailing list hosted by www.jiscmail.ac.uk, terms & conditions are
> available at https://www.jiscmail.ac.uk/policyandsecurity/
>

########################################################################

To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Reply via email to