Dear colleagues,

We are pleased to announce the twentieth release of BioModels Database (

In this release, 65 new models have been published. The public version of BioModels Database now contains 366 models in the curated and 398 in the non-curated branch. Together, these 764 models comprise 119745 species, 135889 relationships (which include reactions, rate rules, events and assignment rules), and 24666 cross-references.

Along with the data release, various performance improvements were made: the loading speed of pages describing models in the non-curated branch should be greatly improved, especially for large models.

For more details about this release, please refer to:

BioModels Database is being developed by the Computational Systems Neurobiology group (EMBL-European Bioinformatics Institute, United Kingdom) and the SBML Team (California Institute of Technology, USA). The collaborators are the Database Of Quantitative Cellular Signalling (National Center for Biological Sciences, India), the Virtual Cell (University of Connecticut Health Center, USA), JWS Online (Stellenbosch University, ZA) and the CellML Team (Auckland Bioengineering Institute, NZ).

BioModels Database development is funded by the European Molecular
Biology Laboratory (Computational Systems Neurobiology group), the UK Biotechnology and Biological Sciences Research Council (Computational Systems Neurobiology group), the National Institute of General Medical Sciences (SBML team and Computational Systems Neurobiology group), and the National Center for Research Resources (Virtual Cell team).

BioModels Database also benefited from the help of Herbert Sauro
(University of Washington, USA) and Hiroaki Kitano (Systems Biology
Institute, Japan), and from the funds of the DARPA (Sauro team).

A big thank you to all collaborators and submitters.

We also want to thank the SBML community for their support and the tools they develop and provide.

Camille Laibe
on behalf of the team.

Camille Laibe Coordinator
European Bioinformatics Institute, Cambridge (UK)
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