Based on what we've seen with perf, we think this is the relevant section.  
(attached is also the whole file)

Thread: 73 (mgr-fin) - 1000 samples 

+ 100.00% clone
  + 100.00% start_thread
    + 100.00% Finisher::finisher_thread_entry()
      + 99.40% Context::complete(int)
      | + 99.40% FunctionContext::finish(int)
      |   + 99.40% ActivePyModule::notify(std::string const&, std::string 
const&)
      |     + 91.30% PyObject_CallMethod
      |     | + 91.30% call_function_tail
      |     |   + 91.30% PyObject_Call
      |     |     + 91.30% instancemethod_call
      |     |       + 91.30% PyObject_Call
      |     |         + 91.30% function_call
      |     |           + 91.30% PyEval_EvalCodeEx
      |     |             + 88.40% PyEval_EvalFrameEx
      |     |             | + 88.40% PyEval_EvalFrameEx
      |     |             |   + 88.40% ceph_state_get(BaseMgrModule*, _object*)
      |     |             |     + 88.40% 
ActivePyModules::get_python(std::string const&)
      |     |             |       + 51.10% 
PGMap::dump_osd_stats(ceph::Formatter*) const
      |     |             |       | + 51.10% osd_stat_t::dump(ceph::Formatter*) 
const
      |     |             |       |   + 22.50% ceph::fixed_u_to_string(unsigned 
long, int)
      |     |             |       |   | + 10.50% std::basic_ostringstream<char, 
std::char_traits<char>, std::allocator<char> 
>::basic_ostringstream(std::_Ios_Openmode)
      |     |             |       |   | | + 9.30% std::basic_ios<char, 
std::char_traits<char> >::init(std::basic_streambuf<char, 
std::char_traits<char> >*)
      |     |             |       |   | | | + 7.00% std::basic_ios<char, 
std::char_traits<char> >::_M_cache_locale(std::locale const&)
      |     |             |       |   | | | | + 1.60% std::ctype<char> const& 
std::use_facet<std::ctype<char> >(std::locale const&)
      |     |             |       |   | | | | | + 1.50% __dynamic_cast
      |     |             |       |   | | | | |   + 0.80% 
__cxxabiv1::__vmi_class_type_info::__do_dyncast(long, 
__cxxabiv1::__class_type_info::__sub_kind, __cxxabiv1::__class_type_info 
const*, void const*, __cxxabiv1::__class_type_info const*, void const*, 
__cxxabiv1::__class_type_info::__dyncast_result&) const
      |     |             |       |   | | | | + 1.40% bool 
std::has_facet<std::ctype<char> >(std::locale const&)
      |     |             |       |   | | | | | + 1.30% __dynamic_cast
      |     |             |       |   | | | | |   + 0.90% 
__cxxabiv1::__vmi_class_type_info::__do_dyncast(long, 
__cxxabiv1::__class_type_info::__sub_kind, __cxxabiv1::__class_type_info 
const*, void const*, __cxxabiv1::__class_type_info const*, void const*, 
__cxxabiv1::__class_type_info::__dyncast_result&) const
      |     |             |       |   | | | | + 1.10% bool 
std::has_facet<std::num_put<char, std::ostreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | | + 0.90% __dynamic_cast
      |     |             |       |   | | | | + 1.00% bool 
std::has_facet<std::num_get<char, std::istreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | | + 0.70% __dynamic_cast
      |     |             |       |   | | | | | + 0.10% 
std::locale::id::_M_id() const
      |     |             |       |   | | | | | + 0.10% 
_ZNKSt6locale2id5_M_idEv@plt
      |     |             |       |   | | | | + 0.80% std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > > const& 
std::use_facet<std::num_put<char, std::ostreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.70% std::num_get<char, 
std::istreambuf_iterator<char, std::char_traits<char> > > const& 
std::use_facet<std::num_get<char, std::istreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.10% 
_ZSt9has_facetISt7num_putIcSt19ostreambuf_iteratorIcSt11char_traitsIcEEEEbRKSt6locale@plt
      |     |             |       |   | | | + 2.00% std::ios_base::_M_init()
      |     |             |       |   | | | | + 0.80% 
std::locale::operator=(std::locale const&)
      |     |             |       |   | | | | + 0.80% std::locale::locale()
      |     |             |       |   | | | | + 0.30% std::locale::~locale()
      |     |             |       |   | | | | + 0.10% _ZNSt6localeC1Ev@plt
      |     |             |       |   | | | + 0.20% _ZNSt8ios_base7_M_initEv@plt
      |     |             |       |   | | + 0.90% std::locale::locale()
      |     |             |       |   | | + 0.10% std::ios_base::ios_base()
      |     |             |       |   | | + 0.10% 
_ZNSt9basic_iosIcSt11char_traitsIcEE4initEPSt15basic_streambufIcS1_E@plt
      |     |             |       |   | + 2.80% std::ostream& 
std::ostream::_M_insert<unsigned long>(unsigned long)
      |     |             |       |   | | + 2.40% std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > 
>::do_put(std::ostreambuf_iterator<char, std::char_traits<char> >, 
std::ios_base&, char, unsigned long) const
      |     |             |       |   | | | + 2.10% 
std::ostreambuf_iterator<char, std::char_traits<char> > std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > 
>::_M_insert_int<unsigned long>(std::ostreambuf_iterator<char, 
std::char_traits<char> >, std::ios_base&, char, unsigned long) const
      |     |             |       |   | | | | + 1.60% 
std::basic_streambuf<char, std::char_traits<char> >::xsputn(char const*, long)
      |     |             |       |   | | | | | + 1.40% 
std::basic_stringbuf<char, std::char_traits<char>, std::allocator<char> 
>::overflow(int)
      |     |             |       |   | | | | | | + 0.90% 
std::string::reserve(unsigned long)
      |     |             |       |   | | | | | | + 0.10% 
std::basic_stringbuf<char, std::char_traits<char>, std::allocator<char> 
>::_M_sync(char*, unsigned long, unsigned long)
      |     |             |       |   | | | | | | + 0.10% 
_ZNSt15basic_stringbufIcSt11char_traitsIcESaIcEE7_M_syncEPcmm@plt
      |     |             |       |   | | | | | + 0.20% __memcpy_ssse3_back
      |     |             |       |   | | | | + 0.20% ???
      |     |             |       |   | | | | + 0.10% std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > >::_M_pad(char, long, 
std::ios_base&, char*, char const*, int&) const
      |     |             |       |   | | | + 0.10% 
_ZNKSt7num_putIcSt19ostreambuf_iteratorIcSt11char_traitsIcEEE13_M_insert_intImEES3_S3_RSt8ios_basecT_@plt
      |     |             |       |   | | + 0.10% 
std::ostream::sentry::sentry(std::ostream&)
      |     |             |       |   | + 2.80% std::basic_stringbuf<char, 
std::char_traits<char>, std::allocator<char> >::str() const
      |     |             |       |   | | + 1.00% 
std::string::assign(std::string const&)
      |     |             |       |   | | + 0.90% char* 
std::string::_S_construct<char*>(char*, char*, std::allocator<char> const&, 
std::forward_iterator_tag) [clone .part.1796]
      |     |             |       |   | + 1.50% std::string::append(char 
const*, unsigned long)
      |     |             |       |   | | + 1.20% std::string::reserve(unsigned 
long)
      |     |             |       |   | |   + 0.60% 
std::string::_Rep::_M_clone(std::allocator<char> const&, unsigned long)
      |     |             |       |   | |   + 0.10% tc_free
      |     |             |       |   | + 1.20% 
std::string::_Rep::_M_dispose(std::allocator<char> const&) [clone .isra.97] 
[clone .part.98]
      |     |             |       |   | + 1.00% std::string::append(std::string 
const&)
      |     |             |       |   | | + 0.70% std::string::reserve(unsigned 
long)
      |     |             |       |   | | + 0.10% __memcpy_ssse3_back
      |     |             |       |   | + 1.00% std::basic_string<char, 
std::char_traits<char>, std::allocator<char> >::basic_string(std::string 
const&, unsigned long, unsigned long)
      |     |             |       |   | | + 0.80% char* 
std::string::_S_construct<char*>(char*, char*, std::allocator<char> const&, 
std::forward_iterator_tag) [clone .part.220]
      |     |             |       |   | + 0.40% std::locale::~locale()
      |     |             |       |   | + 0.20% tc_free
      |     |             |       |   | + 0.20% __strlen_sse2_pminub
      |     |             |       |   | + 0.10% std::ios_base::~ios_base()
      |     |             |       |   | + 0.10% _ZNSt8ios_baseD2Ev@plt
      |     |             |       |   | + 0.10% 
_ZNKSt15basic_stringbufIcSt11char_traitsIcESaIcEE3strEv@plt
      |     |             |       |   + 18.20% 
PyFormatter::open_object_section(char const*)
      |     |             |       |   | + 17.10% PyDict_New
      |     |             |       |   | | + 16.70% _PyObject_GC_New
      |     |             |       |   | |   + 16.70% _PyObject_GC_Malloc
      |     |             |       |   | |     + 16.60% collect
      |     |             |       |   | |     | + 8.10% dict_traverse
      |     |             |       |   | |     | | + 3.20% visit_reachable
      |     |             |       |   | |     | | | + 0.10% type_is_gc
      |     |             |       |   | |     | | + 2.80% visit_decref
      |     |             |       |   | |     | | + 1.60% PyDict_Next
      |     |             |       |   | |     | + 1.30% list_traverse
      |     |             |       |   | |     | | + 0.40% visit_decref
      |     |             |       |   | |     | | + 0.30% visit_reachable
      |     |             |       |   | |     | + 0.60% func_traverse
      |     |             |       |   | |     | + 0.40% _PyDict_MaybeUntrack
      |     |             |       |   | |     | + 0.10% type_traverse
      |     |             |       |   | |     | + 0.10% subtype_traverse
      |     |             |       |   | |     | + 0.10% set_traverse
      |     |             |       |   | |     | + 0.10% class_traverse
      |     |             |       |   | |     | + 0.10% _PyDict_MaybeUntrack@plt
      |     |             |       |   | |     + 0.10% PyObject_Malloc
      |     |             |       |   | + 1.00% PyFormatter::dump_pyobject(char 
const*, _object*)
      |     |             |       |   |   + 0.40% PyString_FromString
      |     |             |       |   |   + 0.20% dict_set_item_by_hash_or_entry
      |     |             |       |   |   + 0.20% PyDict_SetItem
      |     |             |       |   |   + 0.10% app1
      |     |             |       |   + 6.60% 
ceph::Formatter::dump_format_unquoted(char const*, char const*, ...)
      |     |             |       |   | + 6.60% 
PyFormatter::dump_format_va(char const*, char const*, bool, char const*, 
__va_list_tag*)
      |     |             |       |   |   + 3.90% __vsnprintf_chk
      |     |             |       |   |   | + 3.40% vfprintf
      |     |             |       |   |   | | + 0.50% strchrnul
      |     |             |       |   |   | | + 0.40% __GI__IO_default_xsputn
      |     |             |       |   |   | | + 0.20% tc_free
      |     |             |       |   |   | | + 0.10% free@plt
      |     |             |       |   |   | | + 0.10% (anonymous 
namespace)::free_null_or_invalid(void*, void (*)(void*)) [clone .constprop.41]
      |     |             |       |   |   | + 0.20% _IO_no_init
      |     |             |       |   |   | + 0.10% _IO_str_init_static_internal
      |     |             |       |   |   + 1.50% 
PyFormatter::dump_pyobject(char const*, _object*)
      |     |             |       |   |   | + 0.50% PyString_FromString
      |     |             |       |   |   | + 0.40% PyDict_SetItem
      |     |             |       |   |   | + 0.10% 
dict_set_item_by_hash_or_entry
      |     |             |       |   |   | + 0.10% PyDict_SetItem@plt
      |     |             |       |   |   + 1.20% PyString_FromString
      |     |             |       |   |     + 0.60% PyObject_Malloc
      |     |             |       |   |     + 0.20% __strlen_sse2_pminub
      |     |             |       |   |     + 0.10% __memcpy_ssse3_back
      |     |             |       |   + 0.90% ctime_r
      |     |             |       |   + 0.80% 
PyFormatter::open_array_section(char const*)
      |     |             |       |   + 0.40% 
std::string::_Rep::_M_dispose(std::allocator<char> const&) [clone .isra.846] 
[clone .part.847]
      |     |             |       |   + 0.30% PyFormatter::dump_int(char 
const*, long)
      |     |             |       |   + 0.20% PyFormatter::close_section()
      |     |             |       |   + 0.10% tc_free
      |     |             |       |   + 0.10% std::basic_string<char, 
std::char_traits<char>, std::allocator<char> >::basic_string(char const*, 
std::allocator<char> const&)
      |     |             |       |   + 0.10% 
std::_Rb_tree_increment(std::_Rb_tree_node_base const*)
      |     |             |       |   + 0.10% 
pow2_hist_t::dump(ceph::Formatter*) const
      |     |             |       |   + 0.10% 
objectstore_perf_stat_t::dump(ceph::Formatter*) const
      |     |             |       |   + 0.10% PyFormatter::dump_string(char 
const*, std::basic_string_view<char, std::char_traits<char> >)
      |     |             |       |   + 0.10% PyFormatter::dump_pyobject(char 
const*, _object*)
      |     |             |       + 21.80% Mutex::lock(bool)
      |     |             |       | + 21.80% pthread_mutex_lock
      |     |             |       |   + 21.80% _L_lock_883
      |     |             |       |     + 21.80% __lll_lock_wait
      |     |             |       + 11.70% PGMap::dump(ceph::Formatter*) const
      |     |             |       | + 11.70% 
PGMap::dump_pg_stats(ceph::Formatter*, bool) const
      |     |             |       |   + 10.90% 
pg_stat_t::dump(ceph::Formatter*) const
      |     |             |       |   | + 4.20% PyFormatter::dump_stream(char 
const*)
      |     |             |       |   | | + 2.80% std::basic_ios<char, 
std::char_traits<char> >::init(std::basic_streambuf<char, 
std::char_traits<char> >*)
      |     |             |       |   | | | + 2.10% std::basic_ios<char, 
std::char_traits<char> >::_M_cache_locale(std::locale const&)
      |     |             |       |   | | | | + 0.50% std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > > const& 
std::use_facet<std::num_put<char, std::ostreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.50% bool 
std::has_facet<std::num_put<char, std::ostreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.40% bool 
std::has_facet<std::num_get<char, std::istreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.20% std::num_get<char, 
std::istreambuf_iterator<char, std::char_traits<char> > > const& 
std::use_facet<std::num_get<char, std::istreambuf_iterator<char, 
std::char_traits<char> > > >(std::locale const&)
      |     |             |       |   | | | | + 0.20% std::ctype<char> const& 
std::use_facet<std::ctype<char> >(std::locale const&)
      |     |             |       |   | | | | + 0.20% bool 
std::has_facet<std::ctype<char> >(std::locale const&)
      |     |             |       |   | | | | + 0.10% 
_ZSt9has_facetISt7num_putIcSt19ostreambuf_iteratorIcSt11char_traitsIcEEEEbRKSt6locale@plt
      |     |             |       |   | | | + 0.70% std::ios_base::_M_init()
      |     |             |       |   | | + 0.50% 
tcmalloc::ThreadCache::FetchFromCentralCache(unsigned int, int)
      |     |             |       |   | | + 0.40% std::string::assign(char 
const*, unsigned long)
      |     |             |       |   | | + 0.20% std::locale::locale()
      |     |             |       |   | | + 0.10% std::ios_base::ios_base()
      |     |             |       |   | + 1.80% 
object_stat_collection_t::dump(ceph::Formatter*) const
      |     |             |       |   | | + 1.70% 
object_stat_sum_t::dump(ceph::Formatter*) const
      |     |             |       |   | | | + 1.40% 
PyFormatter::dump_pyobject(char const*, _object*)
      |     |             |       |   | | | | + 0.60% dictresize
      |     |             |       |   | | | | + 0.30% PyString_FromString
      |     |             |       |   | | | | + 0.20% PyDict_SetItem
      |     |             |       |   | | | | + 0.10% 
dict_set_item_by_hash_or_entry
      |     |             |       |   | | | + 0.20% PyFormatter::dump_int(char 
const*, long)
      |     |             |       |   | | + 0.10% 
PyFormatter::open_object_section(char const*)
      |     |             |       |   | + 1.80% 
PyFormatter::open_array_section(char const*)
      |     |             |       |   | | + 1.60% PyList_New
      |     |             |       |   | | | + 1.60% _PyObject_GC_New
      |     |             |       |   | | |   + 1.60% _PyObject_GC_Malloc
      |     |             |       |   | | |     + 1.60% collect
      |     |             |       |   | | |       + 0.80% dict_traverse
      |     |             |       |   | | |       + 0.10% subtype_traverse
      |     |             |       |   | | |       + 0.10% list_traverse
      |     |             |       |   | | |       + 0.10% func_traverse
      |     |             |       |   | | |       + 0.10% _PyDict_MaybeUntrack
      |     |             |       |   | | + 0.20% 
PyFormatter::dump_pyobject(char const*, _object*)
      |     |             |       |   | + 1.70% 
utime_t::localtime(std::ostream&) const
      |     |             |       |   | | + 1.00% std::ostream& 
std::ostream::_M_insert<long>(long)
      |     |             |       |   | | | + 0.60% std::num_put<char, 
std::ostreambuf_iterator<char, std::char_traits<char> > 
>::do_put(std::ostreambuf_iterator<char, std::char_traits<char> >, 
std::ios_base&, char, long) const
      |     |             |       |   | | + 0.30% std::basic_ostream<char, 
std::char_traits<char> >& std::__ostream_insert<char, std::char_traits<char> 
>(std::basic_ostream<char, std::char_traits<char> >&, char const*, long)
      |     |             |       |   | | + 0.20% __tz_convert
      |     |             |       |   | + 0.90% PyFormatter::dump_pyobject(char 
const*, _object*)
      |     |             |       |   | + 0.20% pg_state_string(unsigned long)
      |     |             |       |   | + 0.20% operator<<(std::ostream&, 
eversion_t const&) [clone .isra.103]
      |     |             |       |   | + 0.10% std::ostream& 
std::ostream::_M_insert<unsigned long>(unsigned long)
      |     |             |       |   + 0.40% PyFormatter::dump_stream(char 
const*)
      |     |             |       |   + 0.30% operator<<(std::ostream&, pg_t 
const&)
      |     |             |       |   + 0.10% 
PyFormatter::open_object_section(char const*)
      |     |             |       + 2.70% PyFormatter::finish_pending_streams()
      |     |             |       | + 1.00% 
std::_List_base<std::shared_ptr<PyFormatter::PendingStream>, 
std::allocator<std::shared_ptr<PyFormatter::PendingStream> > >::_M_clear()
      |     |             |       | | + 0.40% 
std::_Sp_counted_ptr_inplace<PyFormatter::PendingStream, 
std::allocator<PyFormatter::PendingStream>, 
(__gnu_cxx::_Lock_policy)2>::_M_dispose()
      |     |             |       | | + 0.20% 
tcmalloc::ThreadCache::ListTooLong(tcmalloc::ThreadCache::FreeList*, unsigned 
int)
      |     |             |       | + 0.70% PyFormatter::dump_pyobject(char 
const*, _object*)
      |     |             |       | + 0.50% std::string::replace(unsigned long, 
unsigned long, char const*, unsigned long)
      |     |             |       | + 0.30% PyString_FromString
      |     |             |       + 1.10% PyEval_RestoreThread
      |     |             |         + 1.10% PyThread_acquire_lock
      |     |             |           + 1.10% sem_wait@@GLIBC_2.2.5
      |     |             |             + 1.10% __new_sem_wait_slow.constprop.0
      |     |             |               + 1.10% do_futex_wait.constprop.1
      |     |             + 2.90% frame_dealloc
      |     |               + 2.90% dict_dealloc
      |     |                 + 2.90% list_dealloc
      |     |                   + 2.90% dict_dealloc
      |     |                     + 1.90% list_dealloc
      |     |                     | + 1.90% dict_dealloc
      |     |                     |   + 1.70% list_dealloc
      |     |                     |     + 1.50% dict_dealloc
      |     |                     |     | + 0.90% dict_dealloc
      |     |                     |     | + 0.10% PyObject_Free
      |     |                     |     + 0.10% 
tcmalloc::ThreadCache::ListTooLong(tcmalloc::ThreadCache::FreeList*, unsigned 
int)
      |     |                     + 0.30% PyObject_Free
      |     |                     + 0.20% dict_dealloc
      |     + 8.10% Gil::Gil(SafeThreadState&, bool)
      |       + 8.10% PyEval_RestoreThread
      |         + 8.10% PyThread_acquire_lock
      |           + 8.10% sem_wait@@GLIBC_2.2.5
      |             + 8.10% __new_sem_wait_slow.constprop.0
      |               + 8.10% do_futex_wait.constprop.1
      + 0.60% std::condition_variable::wait(std::unique_lock<std::mutex>&)

--
Paul Mezzanini
Sr Systems Administrator / Engineer, Research Computing
Information & Technology Services
Finance & Administration
Rochester Institute of Technology
o:(585) 475-3245 | [email protected]

CONFIDENTIALITY NOTE: The information transmitted, including attachments, is
intended only for the person(s) or entity to which it is addressed and may
contain confidential and/or privileged material. Any review, retransmission,
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information by persons or entities other than the intended recipient is
prohibited. If you received this in error, please contact the sender and
destroy any copies of this information.
------------------------

________________________________________
From: Mark Nelson <[email protected]>
Sent: Thursday, December 19, 2019 11:47 AM
To: [email protected]
Subject: [ceph-users] Re: High CPU usage by ceph-mgr in 14.2.5

If you can get a wallclock profiler on the mgr process we might be able
to figure out specifics of what's taking so much time (ie processing
pg_summary or something else).  Assuming you have gdb with the python
bindings and the ceph debug packages installed, if you (are anyone)
could try gdbpmp on the 100% mgr process that would be fantastic.


https://github.com/markhpc/gdbpmp


gdbpmp.py -p`pidof ceph-mgr` -n 1000 -o mgr.gdbpmp


If you want to view the results:


gdbpmp.py -i mgr.gdbpmp -t 1


Thanks,

Mark


On 12/19/19 6:29 AM, Paul Emmerich wrote:
> We're also seeing unusually high mgr CPU usage on some setups, the
> only thing they have in common seem to > 300 OSDs.
>
> Threads using the CPU are "mgr-fin" and and "ms_dispatch"
>
>
> Paul
>
> --
> Paul Emmerich
>
> Looking for help with your Ceph cluster? Contact us at https://croit.io
>
> croit GmbH
> Freseniusstr. 31h
> 81247 München
> www.croit.io <http://www.croit.io>
> Tel: +49 89 1896585 90
>
>
> On Thu, Dec 19, 2019 at 9:40 AM Serkan Çoban <[email protected]
> <mailto:[email protected]>> wrote:
>
>     +1
>     1500 OSDs, mgr is constant %100 after upgrading from 14.2.2 to 14.2.5.
>
>     On Thu, Dec 19, 2019 at 11:06 AM Toby Darling
>     <[email protected] <mailto:[email protected]>> wrote:
>     >
>     > On 18/12/2019 22:40, Bryan Stillwell wrote:
>     > > That's how we noticed it too.  Our graphs went silent after
>     the upgrade
>     > > completed.  Is your large cluster over 350 OSDs?
>     >
>     > A 'me too' on this - graphs have gone quiet, and mgr is using
>     100% CPU.
>     > This happened when we grew our 14.2.5 cluster from 328 to 436 OSDs.
>     >
>     > Cheers
>     > Toby
>     > --
>     > Toby Darling, Scientific Computing (2N249)
>     > MRC Laboratory of Molecular Biology
>     > Francis Crick Avenue
>     > Cambridge Biomedical Campus
>     > Cambridge CB2 0QH
>     > Phone 01223 267070
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