Another brain imaging study from germany this time:
J Am Acad Child Adolesc Psychiatry. 1999 Nov;38(11):1363-71.
Atypical frontal brain activation in ADHD: preschool and elementary
school boys and girls.
Baving L, Laucht M, Schmidt MH.
Department of Child and Adolescent Psychiatry and Psychotherapy,
Central Institute of Mental Health, Mannheim, Germany.
[EMAIL PROTECTED]
OBJECTIVE: To investigate patterns of frontal brain activation in
unmedicated preschool and school boys and girls with
attention-deficit/hyperactivity disorder (ADHD). METHOD: Baseline
electroencephalographic activity of 117 children (66 aged 4 years, 51
aged 8 years) was subjected to power spectral analysis, and laterality
scores were determined.
RESULTS:
Boys with ADHD exhibited a less right-lateralized frontal activation
pattern than normal control boys.
Girls with ADHD displayed a more right-lateralized frontal activation
pattern than normal control girls. This finding applied to children at
both 4 1/2 and 8 years of age.
There was no difference between children with ADHD and children with
ADHD plus oppositional defiant disorder.
CONCLUSIONS: This pattern of frontal brain activation is in line with
magnetic resonance imaging studies of ADHD. It could be demonstrated
in children as young as 4 1/2 years, as well as in school-age
children. The opposite direction of asymmetry in boys and girls
stresses the importance of gender-specific analyses in ADHD.
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