http://edition.cnn.com/2008/HEALTH/conditions/07/30/alzheimer.drug/index.html?iref=mpstoryview

"ritish researchers say a new drug could effectively halt the
progression of Alzheimer's disease, offering hope to millions.
Breakthrough drug 'could halt' Alzheimer's

The pioneering research -- a joint initiative between the University
of Aberdeen in the UK and Singapore-based TauRx Therapeutics -- was
announced this week at the Alzheimer's Association International
Conference on Alzheimer's Disease (ICAD 2008) in Chicago.

The product -- remberTM -- is the first drug to act on the "tangles"
discovered by Alois Alzheimer over a century ago. Tangles are made up
of the protein, tau, which forms inside nerve cells in the brain.

According to Aberdeen University, the drug works by dissolving these
tau fibers to prevent a build up of tangles which destroy nerve cells
and neurons critical for memory.

Trials were carried out on 321 people with mild and moderate
Alzheimer's disease in the UK and Singapore. Patients with mild to
moderate Alzheimer's disease were given either 30, 60 or 100mg of the
drug or a placebo.

The 60mg dose produced the most pronounced effect, with those with
both mild and moderate Alzheimer's experiencing an 81 percent
reduction in mental decline after 50 weeks.

Those on rember did not experience a significant decline in their
mental function over 19 months, while those on placebo got worse."

Good news, go science go. :)

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