Genetically Modified is kind of a catch all phrase for a bunch of
different work. Historically, there was selective breeding that used a
strong selection model (killing off anything that didn't go the
direction you wanted like sweeter or more cold tolerant) and breeding
the few remaining individuals to try and maximize a particular trait
in that strain.

Then there is the sort of genetic modification that Monsanto did with
Roundup. Roundup works by blocking a necessary plant enzyme (I don't
remember what it is called) and Monsanto found a variation in the gene
that produces this enzyme that would not be blocked by Roundup. This
variation is really pretty rare, so what they did was to take it,
synthesize it and then splice it into the genome of plants you do want
to grow, like say, corn. This is a direct manipulation of the genome
for that plant but it isn't that it used a sequence that was entirely
made up or anything. There is resistance to Roundup building out in
the wild, actually, because while the trait is quite rare, the
selective pressure put in place by the use of Roundup has made the
trait flourish wherever it can be acquired.

There is also the next step in GM, which is transgenic organisms. The
most well known of these are seeds which have had Bt (baccilus
thurugensis) genes spliced into their genetic sequence. Bt produces,
naturally, a pesticide that is pretty effective against a number of
common pests. Scientists isolated the genes that code for production
of the compound and were able to incorporate them into plants, thus
enabling the plants to produce the compound themselves.

Genetic Modification, then, really represents a spectrum of techniques
but all have underlying them the decision to directly manipulate the
genetic code instead of letting chance (through breeding) do the
manipulation. This can end up mimicking things that might happen in
the wild anyway (in the case of Roundup resistance) but much faster
and more directly or produce results that almost certainly would never
come up in the wild, like Bt in corn.

Hope that helps,
Judah

On Mon, Jun 7, 2010 at 11:11 AM, Medic <[email protected]> wrote:
>
> Well I think GM is completely different as you can modify genes to get
> combinations that you couldn't really get from breeding.
> I think I'll just wait until Judah drops some science on us and make me feel
> intellectually inadequate through no fault of his own.
>
> /me waits
>

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