We must fight this bacteria before it grows, spreads, and takes over all of
the worlds caffeine. The fate of civilization may depend on it! :)

New Bacteria Lives on Caffeine
http://www.scientificamerican.com/blog/post.cfm?id=new-bacteria-lives-on-caffeine-2011-05-24

Think you live on caffeine? You're still no match for a newly described
bitty bacteria called Pseudomonas putida CBB5. These little guys can feast
on pure caffeine all day—and presumably all night—long. And researchers have
now located just how they accomplish this arguably admirable feat.

Celebrated and cursed, caffeine is actually an alluring blend of carbon,
hydrogen, nitrogen and oxygen, and the clever bacterium uses specialized
enzymes as it "breaks caffeine down into carbon dioxide and ammonia," Ryan
Summers, a doctoral researcher in Chemical and Biochemical Engineering at
the University of Iowa, said in a prepared statement.

Summers and his colleagues found these caffeine-feeding bacteria lolling in
a flowerbed on the University of Iowa campus. Although that hardly seems
like a logical place for such a stimulated species, Summers explained that
it is far from jolting. "Due to the extensive presence of caffeine in the
environment, it is not surprising that there are bacteria that can 'eat'
this molecule for growth and reproduction," he wrote in a summary of his new
research, set to be presented May 24 at the 111th General Meeting of the
American Society for Microbiology in New Orleans.

And the finding could some day have implications outside of a highly
caffeinated Petri dish (although it's unclear whether caffeine gets the
bacteria just as hopped up as it does some humans). "This work, for the
first time, demonstrates the enzymes and genes utilized by bacteria to live
on caffeine," Summers said, noting that previous research had located
caffeine consumption in other microbe species before.

After isolating the suspected genes, the research team inserted them into E.
coli strains, which then manufactured the caffeine-digesting enzymes
(N-demethylase named NdmA and NdmB).

Summers and his collaborators noted that the enzymes might be useful to
develop new medications to treat heart arrhythmias or asthma, or to boost
blood flow. The bacteria-generated enzymes could also be scaled up to help
break down excess caffeine generated by industry during decaf coffee and tea
processing.

But back to living on caffeine: How soon can we expect to see coffee-to-go
joints jumping into the research ring?

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