Offhand, using a placeholder and a series of replace()'s will work:

replace(text, 'g', '|', 'all')
replace(text, 'c', 'g', 'all')
replace(text, '|', 'c', 'all')
replace(text, 'a', '|', 'all')
replace(text, 't', 'a', 'all')
replace(text, '|', 't', 'all')

replacelist() may work.  I'm not sure if it's serial for each item in
the list or parallel, and I'm too lazy to investigate.  :-)

--Ben


Richard Colman wrote:
> I need to to reverse compliment a nucleotide sequence, so
> 
> C become a G
> G becomes a C
> A becomes a T
> T becomes an A
> 
> I need to go through a string a character at a time and build a new string.
> 
> So:
> 
> "ACTG" becomes "TGAC"
> 
> Is there an easy way to do this?
> 
> 
> Richard Colman
> Institute for Genomics and Bioinformatics
> 949-824-1816, 701-5330
> [EMAIL PROTECTED]
> 
> 
> 
> 

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